29 citations
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November 2021 in “FEBS Open Bio” In this study, molecular docking simulations and cell-based assays suggested that certain analogues of cepharanthine might possess anti-SARS-CoV-2 activity.
April 2024 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study examined how varying concentrations of kaolin base in mud masks with red pomegranate peel extract influenced properties like viscosity, pH, and drying time, finding that a formulation with 22.5% kaolin performed best in terms of physical characteristics and enzyme inhibition.
In this experimental study, hibiscus leaf extract at a 30% concentration showed effectiveness in promoting hair growth on guinea pigs, with measurable increases in hair length and weight by the 21st day.
4 citations
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October 2024 in “International Journal of Molecular Sciences” In this study, topical naringin was found to significantly improve dermatitis severity and reduce inflammatory markers in a mouse model of atopic dermatitis, suggesting its potential as a therapeutic agent for this condition.
10 citations
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June 2019 in “Dermatologic therapy” In this study, treatment with DPCP alone was more effective for hair regrowth and presented fewer side effects in chronic extensive alopecia areata compared to combination therapy with DPCP and anthralin.
20 citations
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June 2019 in “Archives of dermatological research” In this study, combination therapy with DPCP and anthralin promoted hair regrowth in 40.62% of alopecia areata patients who were unresponsive to DPCP alone, with response improving over longer treatment durations.
44 citations
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January 2007 in “Biological & pharmaceutical bulletin” This study found that Piper nigrum leaf extract showed in vivo anti-androgenic activity and potent 5α-reductase inhibitory effects, with piperine and (−)-cubebin identified as active components.
In this study, 1% pimekrolimus cream was found to be more effective than 0.05% clobetasol propionate for treating active plaques in patients with alopecia areata.
26 citations
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October 2019 in “JNCI Cancer Spectrum” This clinical study observed that in patients with advanced breast cancer and BRCA1/2 mutations, talazoparib provided significantly better progression-free survival, objective response, clinical benefit, and patient-reported outcomes compared to physician’s choice chemotherapy, despite common side effects like anemia and fatigue.
15 citations
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January 2014 in “Medicinal chemistry” This study conducted molecular docking and ADME property analysis on 144 newly designed isatin analogs, suggesting they exhibit lead-like properties for targeting EGFR enzymes.
January 2026 in “RSC Advances” Panax notoginseng may help with oral ulcers and hair growth.
June 1993 in “Current opinion in therapeutic patents” This study reports that novel hexahydrobenzoquinolin compounds fully inhibited 5α-reductase activity in human genital skin fibroblasts, suggesting their potential for treating conditions like benign prostatic hyperplasia and male pattern baldness.
9 citations
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June 2022 in “Reviews in Environmental Science and Bio/Technology” This review discusses the industrial applications of maritime pine by-products, emphasizing their antioxidant and antimicrobial properties, and suggests innovation opportunities in a circular economy context; it reports no new results.
3 citations
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March 2012 in “Arab Journal of Urology” This study found that cromakalim and pinacidil significantly inhibited porcine detrusor muscle contractions, suggesting these ATP-sensitive potassium channel openers may have potential in treating certain bladder diseases.
October 2019 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a new solution called CapilGen, showing it increased hair quantity by 35% and density by 25% in clinical trials without side effects, providing a potentially safe and effective treatment for baldness.
May 2026 in “International Journal of Research Publication and Reviews” The researchers reported that a polyherbal hair dye using Phyllanthus reticulatus fruit provided effective color, stability, and scalp compatibility without irritation, positioning it as a safe and eco-friendly alternative to synthetic dyes.
20 citations
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January 2003 in “Dermatology online journal” This review discusses the potential of prostaglandin analogs for hair growth and forms of alopecia, and reports no new clinical results.
December 2023 in “Reactions weekly” December 2023 in “Reactions weekly” September 2013 in “Reactions weekly”
2 citations
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December 2013 in “Xenobiotica” This study found that the metabolic profile of finasteride in pigs closely matches that of humans, supporting the use of pigs for studying human drug metabolism.
9 citations
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” This letter reports repigmentation of hair in patients receiving latanoprost therapy.
11 citations
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January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
1 citations
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November 2021 in “Jurnal Farmasi Indonesia” In this study, three hair tonic formulas containing Kayu Secang extracts demonstrated hair growth activity in rabbits, with the chloroform-methanol fraction showing the most significant results.
September 2022 in “Frontiers in Bioengineering and Biotechnology” This study reports that taxifolin from enzymatic hydrolysis effectively regulates dermal papilla cell apoptosis and promotes hair growth by increasing IGF-1 and reducing TGF-β1, though it shows less inhibition of DHT compared to minoxidil.
162 citations
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August 2002 in “Survey of Ophthalmology” This study found that latanoprost induces significant growth and pigmentation of lashes and ancillary hairs, with effects mirroring both brief and chronic treatments observed in patients and animal models.
January 2022 in “Elsevier eBooks” This study found that sodium valproate nanospanlastics could be an effective and safer method for treating androgenic alopecia, with results comparable to minoxidil but fewer side effects.
22 citations
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March 2003 in “Steroids” This study found that both finasteride and a new steroidal compound, PM-9, competitively inhibit the 5α-reductase enzyme in Penicillium crustosum broth.
December 2025 in “Biomolecules” In this study, the synthesis and testing of new pyrroloquinoline derivatives identified compound 7p, which showed low micromolar cytotoxic activity against MCF-7 and HeLa cells, highlighting its potential for development into a potent anticancer agent.
April 2011 in “Cancer Research” In this study, ginsenoside 20(S)-protopanaxadiol-aglycone (PPD) was shown to downregulate androgen receptor expression and inhibit tumor growth in prostate cancer cells.