299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
237 citations,
June 2013 in “Nature Medicine” A protein from certain immune cells is key for new hair growth after skin injury in mice.
223 citations,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
182 citations,
August 2018 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
92 citations,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
83 citations,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
46 citations,
November 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
35 citations,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
29 citations,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
25 citations,
September 2020 in “Molecules” Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
24 citations,
June 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
22 citations,
May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
19 citations,
May 2015 in “Stem Cells” Pro-IGF-II improves muscle repair in old mice.
8 citations,
June 2022 in “Frontiers in bioengineering and biotechnology” A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
April 2024 in “Research Square (Research Square)” MSC-protein helps regenerate gum tissue and bone.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
June 2023 in “Journal of multidisciplinary sciences (Online)” PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
July 2020 in “Journal of Investigative Dermatology” The technique effectively shows how human skin and hair cells form into ball-like structures.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
300 citations,
October 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
77 citations,
August 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
76 citations,
October 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
57 citations,
May 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
42 citations,
October 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
38 citations,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
35 citations,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
30 citations,
February 2019 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
14 citations,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
9 citations,
January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.