June 2023 in “Journal of multidisciplinary sciences (Online)” This review examines possible links between polycystic ovarian syndrome and reproductive cancers, but reports no new clinical findings.
March 2022 in “Pakistan BioMedical Journal” This study found that many adolescent girls in Pakistan were unaware of their PCOS symptoms, which are associated with a high prevalence and may be linked to dietary habits affecting menstrual cycles.
September 2021 in “International Journal of Biomedicine” This study found that SNPs in the MVK, ARPC1B, and CA2 genes may indicate a genetic predisposition for severe acne related to steroidogenesis.
April 2021 in “Journal of evolution of medical and dental sciences” This study found that bioavailable testosterone and the free androgen index were significantly associated with various clinical and biochemical features of PCOS, including hirsutism, showing higher levels in PCOS patients compared to controls.
January 2016 in “Springer eBooks” Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.
April 2014 in “Journal of Aesthetic Nursing” This article provides descriptive results indicating high client satisfaction and good tolerance associated with mesotherapy in treating hair loss, based on the author's personal experience with clients.
October 2015 in “Elsevier eBooks” Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
August 2002 in “Zeitschrift für Hautkrankheiten” This review discusses female pattern hair loss, suggesting it involves both androgen-dependent and independent factors, but it reports no new clinical results.
5 citations
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March 2015 in “Clinical and Experimental Dermatology” This case report describes a 22-year-old woman who developed persistent, non-scarring hair loss and premature ovarian failure following a myeloablative umbilical cord transplant for acute myeloid leukemia.
January 2024 in “La Ciencia al Servicio de la Salud y Nutrición” This narrative review attributes antiandrogenic properties to spironolactone, reporting its effectiveness in treating dermatological conditions like alopecia androgenica, acne, and hirsutism, though highlighting necessary attention to potential adverse effects and contraindications.
February 2014 in “Medicine - Programa De Formación Médica Continuada Acreditado” This paper reviews various types of scarring and non-scarring alopecia, including their etiology, diagnosis, and treatment, but it reports no new clinical results.
29 citations
,
October 1988 in “Journal of Steroid Biochemistry” This review discusses the use of antiandrogens for various conditions like prostate cancer and highlights their potential benefits in remission rates and symptom improvement, but it reports no new clinical results.
23 citations
,
May 2009 in “International Journal of Dermatology” In this study, no association was found between the AR gene and type II androgenetic alopecia in Egyptian women, suggesting it is not a useful biomarker for predisposition.
17 citations
,
February 2003 in “Australasian Journal of Dermatology” This review discusses ovarian hyperthecosis as a rare cause of androgenetic alopecia in postmenopausal women and reports no new results; the authors highlight the need to explore its relationship to alopecia further.
12 citations
,
December 2012 in “Current Drug Targets” The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
12 citations
,
May 2005 in “Current obstetrics and gynaecology/Current obstetrics & gynaecology” This review discusses the causes and treatment strategies for hirsutism, emphasizing that combination therapy targeting androgen suppression and hair removal techniques is most effective; no new clinical results are reported.
9 citations
,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” In this study, children with classical congenital adrenal hyperplasia were found to have increased epicardial fat thickness, which was associated with subclinical atherosclerosis markers and left ventricular dysfunction, especially in poorly controlled cases.
8 citations
,
September 2018 in “Journal of Cosmetic Dermatology” This study found that serum irisin levels were significantly lower in patients with acne vulgaris compared to healthy controls and were negatively correlated with insulin resistance and disease severity.
5 citations
,
January 2015 in “Evidence-based complementary and alternative medicine” The authors concluded that the combination of 755 nm alexandrite laser and topical licorice is more effective than the alexandrite laser alone in reducing idiopathic hirsutism in women, with no serious adverse reactions reported.
October 2018 in “Journal of Clinical Research in Pediatric Endocrinology” This study found that children with classic congenital adrenal hyperplasia had elevated epicardial fat thickness, which was associated with increased carotid intima media thickness, left ventricular mass, and mitral deceleration time.
405 citations
,
May 2007 in “Journal of The American Academy of Dermatology” This review discusses the profound impact of obesity on skin physiology and dermatologic conditions and reports no new experimental results, recommending awareness and treatment strategy development for obesity-associated dermatoses.
208 citations
,
July 2001 in “Journal of The American Academy of Dermatology” This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.
91 citations
,
May 2005 in “The Journal of Clinical Endocrinology & Metabolism” In this study, a novel mutation in the glucocorticoid receptor gene was identified in a young woman, impairing glucocorticoid signaling and leading to generalized glucocorticoid resistance.
86 citations
,
October 2017 in “Translational pediatrics” This review discusses how ophthalmic findings can reveal key endocrine disorders and reports no new clinical results, emphasizing the eye's role in diagnosing and managing systemic diseases like diabetes and Graves' ophthalmopathy.
65 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.
59 citations
,
March 2020 in “Journal of Biomedical Science” This study explored the complex roles of niche cells in regulating hair follicle stem cells, identifying specific cell functions such as signaling, sensing, and relaying messages, which could provide insights into treating hair loss conditions like androgenetic alopecia and alopecia areata.
41 citations
,
June 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.
32 citations
,
January 2010 in “Journal of Korean Medical Science” This case report describes a rare instance of functioning adrenocortical oncocytoma in a 14-year-old girl with virilization and reviews related literature.
23 citations
,
January 2019 in “International Journal of Dermatology” This review found that while finasteride may improve female pattern hair loss and hirsutism in women, more long-term studies are needed to optimize its use and assess potential consequences.
17 citations
,
April 1997 in “Archives of dermatology” This case report describes the treatment of hirsutism in a 15-year-old obese Mexican girl with flutamide, aiming to improve her social function.