Complementary Therapies for Idiopathic Hirsutism: Topical Licorice as a Promising Option

    January 2015 in “ Evidence-based complementary and alternative medicine ”
    Gita Faghihi, Fariba Iraji, Bahareh Abtahi‐Naeini, Bahar Saffar, Ali Saffaei, Mohsen Pourazizi, Abolfazl Aslani, Mohammad Ali Nilforoushzadeh
    Image of study
    TLDR Adding licorice gel to laser treatment is more effective for reducing facial hair than laser alone.
    The study conducted a double-blind, randomized placebo-controlled trial on 90 female subjects to compare the effectiveness of 755 nm alexandrite laser hair removal alone versus the combination of alexandrite laser with 15% topical licorice gel in treating idiopathic hirsutism. Subjects were divided into two groups: one received the laser treatment plus licorice gel (group A), and the other received laser treatment plus a placebo (group B). Treatments were applied to two separate zones on the face, twice daily for 24 weeks, with five laser sessions at 6-week intervals. The results showed a statistically significant reduction in the mean number of terminal hairs in group A compared to group B (p < 0.001), with no serious adverse reactions reported. The study concluded that the combination of alexandrite laser and topical licorice is more effective than laser treatment alone for idiopathic hirsutism.
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