TLDR A rare adrenal tumor in a 14-year-old girl caused male-like symptoms and was successfully removed.
A rare case of functioning adrenocortical oncocytoma was reported in a 14-year-old female who exhibited symptoms of virilization, such as deepening of the voice and excessive hair growth, along with elevated levels of plasma testosterone and dehydroepiandrosterone sulfate. The patient underwent an adrenalectomy, and the tumor, which was composed mainly of oncocytes without atypical mitosis and necrosis, was completely resected. This case added to the limited number of childhood cases documented in the literature, highlighting the rarity of this condition in younger patients.
85 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
August 2017 in “Journal of pediatric surgery case reports” A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.
4 citations
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November 2013 in “Journal of IMAB - Annual Proceeding (Scientific Papers)” A rare adrenal tumor in a 9-year-old girl was successfully treated with surgery.
16 citations
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August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
6 citations
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March 2021 in “Frontiers in surgery” A woman's symptoms of increased body hair and testosterone were caused by a rare adrenal tumor, which was removed successfully.
July 2019 in “Journal of the ASEAN Federation of Endocrine Societies” The woman had a rare adrenal tumor removed, and she recovered well with no signs of the tumor returning.
