TLDR A rare adrenal tumor in a 14-year-old girl caused male-like symptoms and was successfully removed.
A rare case of functioning adrenocortical oncocytoma was reported in a 14-year-old female who exhibited symptoms of virilization, such as deepening of the voice and excessive hair growth, along with elevated levels of plasma testosterone and dehydroepiandrosterone sulfate. The patient underwent an adrenalectomy, and the tumor, which was composed mainly of oncocytes without atypical mitosis and necrosis, was completely resected. This case added to the limited number of childhood cases documented in the literature, highlighting the rarity of this condition in younger patients.
85 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
August 2017 in “Journal of pediatric surgery case reports” A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.
April 2024 in “JCEM case reports” A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.
4 citations
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November 2013 in “Journal of IMAB - Annual Proceeding (Scientific Papers)” A rare adrenal tumor in a 9-year-old girl was successfully treated with surgery.
16 citations
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August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
7 citations
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January 2014 in “Case reports in endocrinology” A woman's excessive hair growth was caused by a rare benign tumor in her adrenal gland, which was successfully removed.
