1 citations
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January 2021 in “Journal of V. N. Karazin Kharkiv National University: Series Medicine” This review discusses recent research on androgenetic alopecia's etiology and pathogenesis, highlighting both androgenic and nonandrogenic factors but reports no new experimental results.
1 citations
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January 2018 in “Skin appendage disorders” This review discusses the role of the complement pathway in alopecia areata and reports no new clinical results; the authors suggest that targeting this pathway could offer treatment options.
August 2026 in “International Journal of Research in Medical Sciences” This article reviews how epigenetic modifications, particularly DNA methylation, histone modification, and non-coding RNA pathways, affect the development of skin diseases, suggesting potential for personalized treatments that target these changes.
February 2026 in “Journal of Advances in Biology & Biotechnology” This review highlights advances in understanding alopecia areata as a systemic disease involving genetic, immune, and environmental factors, noting new treatments like Janus kinase inhibitors but acknowledging challenges in long-term safety and accessibility.
September 2025 in “Journal of the American Academy of Dermatology” Reducing SFRP1 can promote hair growth and may help treat hair loss.
March 2025 in “Clinical Reviews in Allergy & Immunology”
January 2025 in “BioMed Research International” This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.
December 2024 in “Iraqi journal of Medical Sciences” This study found that women with PCOS had significantly lower vitamin D levels and higher serum prolactin and testosterone than women without PCOS, suggesting a link between vitamin D deficiency and PCOS symptom severity.
January 2024 in “Elsevier eBooks” The authors concluded that increasing regulatory T cells in patients with alopecia areata may improve hair follicle regeneration by reducing autoimmune responses, suggesting a potential new therapeutic approach since current treatments are often ineffective with high relapse rates.
January 2023 in “Journal of Ravishankar University” This review discusses the role of oxidative stress and reactive oxygen species in the development of androgenic alopecia and reports no new clinical findings.
This study identified a genetic locus associated with rhabdomyosarcoma susceptibility in mice and found that specific differentiation markers are linked to the regression of basal cell carcinoma.
This study found that a single 8Gy dose of superficial 50kV X-ray radiation minimizes keloid recurrence after excision, and identified genomic pathways and potential molecular targets for improved keloid therapy.
April 2017 in “Journal of Investigative Dermatology” This research explores the potential role of the Stx17 protein in hair pigmentation processes and Alopecia Areata, suggesting possible links to the disease's progression.
March 2015 in “Zagazig University Medical Journal” The study found that CK15 expression, representing hair follicle stem cell activity, was reduced or absent in scarred primary cicatricial alopecia lesions, suggesting stem cell damage may contribute to the scarring process.
February 1981 in “Kazan medical journal” This article reviews the research history linking zinc deficiency to hair loss and mucous membrane changes but reports no new clinical results.
November 2017 in “British Journal of Dermatology” Genes controlling hair growth and immune response are disrupted in male pattern baldness.
This study presents a new model for the progression of androgenetic alopecia, suggesting that the loss of attachment between the bulge's stem cells and the arrector pili muscle may contribute to irreversible hair miniaturization.
January 1996 in “Springer eBooks” Hair can regrow if the sebaceous gland is intact, even if the hair root is removed.
This study found that personality characteristics are significantly related to the severity, duration, and pattern of androgenetic alopecia in women.
112 citations
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January 2013 in “Experimental dermatology” This article offers a viewpoint on hidradenitis suppurativa pathogenesis, suggesting that impaired Notch signalling from γ-secretase mutations may drive inflammation and link the condition to other Th17-driven diseases.
100 citations
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November 2021 in “Cell Research” This study found that SARS-CoV-2 hijacks the host factor IGF2BP1 to stabilize its RNA and enhance translation, and identified Cepharanthine and Trifluoperazine as potential treatments against the virus.
99 citations
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.
68 citations
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May 2016 in “Experimental dermatology” This review discusses what is known about the pathobiology of frontal fibrosing alopecia and reports no new clinical findings, highlighting potential environmental and genetic factors in disease pathogenesis.
59 citations
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July 2015 in “Journal of Immunology” This study found that disrupting inflammasome signaling by eliminating caspase-1 and -11 in mice reduced skin inflammation and delayed the onset of disease, highlighting their role in skin disease pathogenesis.
38 citations
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May 2021 in “International Journal of Infectious Diseases” This study found that lower testosterone levels in male COVID-19 patients were associated with greater disease severity and longer hospital stays.
30 citations
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July 2023 in “Journal of Cutaneous Medicine and Surgery” This article emphasizes the need for dermatology to treat gender identity, gender, and sex as distinct factors, aiming to improve patient-specific risk assessment and treatment alignment, and highlights a research gap in distinguishing sex and gender as separate risk factors in the field.
29 citations
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March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
21 citations
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October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified specific germline and somatic mutations in the Phospholipase C Delta 1 gene as high-risk factors for developing hereditary trichilemmal cysts, involving a monoallelic two-hit mechanism.
15 citations
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October 2022 in “Allergy” This study found that dupilumab treatment in alopecia areata significantly suppressed Th2-related markers and increased hair keratin levels, suggesting a potential role of Th2 cytokines in the disease's pathogenesis.
7 citations
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November 2023 in “Microorganisms” This study suggests that the intestinal microbiota may have protective effects against celiac disease by degrading gluten and maintaining intestinal barrier integrity, but disruptions in the microbiota can exacerbate the disease.