4 citations
,
October 2022 in “Genes” This review discusses the role of cutaneous and intestinal microbiota in the development of alopecia areata, summarizing current literature without reporting new clinical results.
4 citations
,
July 2019 in “Children (Basel)” This review discusses recent findings on pathogenic mechanisms, diagnostic criteria, and treatment options for PCOS but reports no new clinical results.
3 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This research suggests that innate lymphoid cells type 1 (ILC1) may contribute to the development of alopecia areata, alongside CD8+ T cells, by disrupting hair follicle immune privilege and promoting features of the disease.
2 citations
,
July 2022 in “Frontiers in Medicine” This review discusses the current understanding of frontal fibrosing alopecia's pathogenesis, highlighting genetic susceptibility, immune response involvement, and possible links to steroid hormones, but reports no new clinical results.
2 citations
,
January 2004 in “Medical Hypotheses” This hypothesis proposes that fungal infection may be a common risk factor for both male pattern baldness and coronary heart disease, supported by some evidence linking antifungal treatment to improvements in both conditions.
1 citations
,
May 2025 in “Clinical Reviews in Allergy & Immunology” 1 citations
,
May 2024 in “International Journal of Molecular Sciences” This study suggests that targeting adenosine receptors could be an effective strategy for reducing inflammation in inflammatory skin disorders, with promising results observed in animal models.
May 2026 in “Frontiers in Immunology” This review discusses the dual role of extracellular vesicles in the pathophysiology and treatment of atopic dermatitis but reports no new clinical results; future research should address standardization and safety challenges.
April 2026 in “Biomedicines” This study introduces a novel holistic treatment approach for keloid that combines systemic therapies, including Traditional Chinese Medicine, with local interventions to target the inflammatory microenvironment and keloid predisposition for improved management and prevention of recurrence.
March 2026 in “Biomedicines” This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.
December 2025 in “Al-Iraqia Medical College Journal” This study explored the relationships between virus susceptibility to infection and several factors, finding that higher heat tolerance and larger virus size correlated positively with infection susceptibility, while high humidity and higher mutation rates correlated inversely among eight RNA viruses, including SARS-CoV-2 and influenza.
November 2025 in “Journal of Investigative Dermatology” A new genetic mutation causing Xeroderma Pigmentosum was found in an 8-year-old girl, affecting her DNA repair.
August 2025 in “Drug Design Development and Therapy” This review article examines current drugs for androgenetic alopecia, focusing on their mechanisms and clinical efficacy, noting that while finasteride and minoxidil are commonly approved treatments, new drugs targeting different pathogenic pathways have emerged, offering a broader understanding and reference for AGA treatment options.
May 2025 in “The FASEB Journal” This study concluded that TNFRSF1B is a potential pathogenic factor in androgenetic alopecia, suggesting it as a novel therapeutic target.
December 2024 in “Clinical Cosmetic and Investigational Dermatology” This study found that AA may have a protective role in the progression of both HBDC and CRC, suggesting potential new research avenues for treatments of these conditions.
July 2024 in “Journal of Investigative Dermatology” Expanding regulatory T cells may help treat alopecia areata by reducing harmful immune cells.
March 2024 in “International journal of molecular sciences” In this study, researchers identified three pathogenic de novo genetic variants contributing to epidermolysis bullosa simplex in young children, highlighting the complexity of genetic influences and underscoring the need for early genetic screening for accurate diagnosis and effective management.
February 2024 in “Journal of Health Science and Medical Therapy” This review discusses the role of ADAM 17 in gynecological disorders, particularly PCOS, and suggests its potential for therapeutic intervention, but reports no new clinical results.
273 citations
,
July 2020 in “British Journal of Dermatology” This review discusses recent insights into the role of regulatory T cells in psoriasis and the impact of current treatments on their function, but reports no new research findings.
171 citations
,
October 1990 in “Alcoholism/Alcoholism, clinical and experimental research” The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
149 citations
,
January 2011 in “Nature reviews. Urology” Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
33 citations
,
April 2021 in “Journal of Dermatological Treatment” New ways to treat acne are being discovered.
33 citations
,
August 2015 in “F1000Research” This study presents a new model for androgenetic alopecia progression, explaining diffuse hair loss in women through 3D reconstructions of the arrector pili muscle and its relationship with the hair follicle stem cell niche.
33 citations
,
April 2012 in “British Journal of Dermatology” This review discusses the role of stem cells in alopecia pathogenesis, highlighting the differences between scarring and nonscarring types, and reports no new clinical results.
29 citations
,
January 2016 in “Disease Markers” This study found that IGF-I and survivin may play a role in the pathogenesis of active acne vulgaris and postinflammatory acne scars, with a significant correlation between their serum levels.
24 citations
,
November 2016 in “Molecular Medicine Reports” This study found that women with acne resistant to conventional treatments had significantly higher levels of testosterone, DHEA‑S, prolactin, and LH, suggesting potential underlying hormonal disorders.
21 citations
,
October 2009 in “Molecular Biology Reports” 16 citations
,
August 1989 in “Human Reproduction” This article discusses the complex pathogenesis of hirsutism and reports no new clinical results; further research is needed for better diagnostic and therapeutic strategies.
8 citations
,
April 2024 in “The Journal of Dermatology” This study suggests that neuropeptides may contribute to the progression of alopecia areata by causing neurogenic inflammation and disrupting the inflammatory environment of hair follicles, but the exact pathogenesis still requires further investigation.
4 citations
,
January 2010 This study found significant reductions in zinc, copper, and iron levels in patients with idiopathic telogen effluvium compared to healthy controls, suggesting a potential role for trace element deficiency in the condition.