September 2023 in “Chinese Journal of Integrative Nursing” This article discusses Traditional Chinese Medicine approaches to treating alopecia areata, outlining etiology, treatment stages, and methods, but does not report new clinical results.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study using a genetic mouse model found that S. aureus-driven dysbiosis sustains inflammatory skin side effects from EGFR inhibitors, suggesting prophylactic antibiotic treatment may reduce rash severity without fixing barrier defects.
December 2010 in “Elsevier eBooks” This article discusses the clinical manifestations of systemic lupus erythematosus and their potential mechanisms, but reports no new experimental results.
This review highlights Malassezia's dual role as both protective and pathogenic within the hair follicle ecosystem, noting its involvement in skin disorders and potential cancer progression, and calls for further studies to develop targeted treatments for related conditions.
May 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that patients with alopecia areata had significantly lower serum levels of autophagy-related protein 5, indicating a potential role of dysfunctional autophagy in the disease's pathogenesis.
October 2025 in “Science Advances” In this study, researchers demonstrated that CD4 T cells from skin-draining lymph nodes in mice with alopecia areata can transfer the disease to recipient mice, revealing a critical role for CD4 T cells in disease development and suggesting potential therapeutic targets.
April 2023 in “The Egyptian Journal of Hospital Medicine” This case control study investigated serum IL-17A levels in alopecia areata patients compared to healthy controls to explore its potential role in the disease's pathogenesis.
October 2021 in “Dermatology Reports” This study found that serum IL-17A levels were significantly higher in patients with alopecia areata compared to healthy controls and correlated with disease severity and activity.
July 2018 in “Benha Journal of Applied Sciences” In this study, researchers found that patients with alopecia areata had significantly higher levels of miR-203 in their skin compared to healthy controls.
December 2022 in “Frontiers in Microbiology” This study found that individuals with androgenetic alopecia had higher scalp microbiome diversity and more complex scalp-gut microbiome networks than those without, suggesting a link between skin-gut microorganisms and hair loss development.
185 citations
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June 2014 in “Journal of Investigative Dermatology” This case report describes complete hair regrowth in a patient with alopecia universalis and improved psoriasis after treatment with the oral Janus kinase inhibitor, tofacitinib.
127 citations
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April 1999 in “Journal of Investigative Dermatology” This review compares various rodent models that reflect aspects of psoriasis with human psoriasis and potential applications for research, reporting no new clinical findings.
62 citations
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June 2015 in “The Journal of Dermatology” This study found that patients with alopecia areata had higher levels of Th17 cells and lower levels of regulatory T cells compared to healthy controls, suggesting an immune imbalance in these patients.
49 citations
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March 2014 in “Dermatologic clinics” This article discusses the causes, development, treatment, and prevention strategies for pseudofolliculitis barbae and folliculitis keloidalis nuchae, but reports no new clinical results.
49 citations
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August 2007 in “Dermatologic surgery” This review discusses newer therapeutic techniques for treating postacne scarring, highlighting their effectiveness for particular grades of scars, and reports no new clinical results.
44 citations
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February 2017 in “Journal of the American Academy of Dermatology” This study found that postmenopausal women with lichen planopilaris showed a high prevalence of androgen excess, while women with frontal fibrosing alopecia were often associated with androgen deficiency.
43 citations
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May 2011 in “Dermatologic therapy” This study identified at least eight genetic regions associated with alopecia areata, which may lead to the development of new targeted therapies based on these findings.
38 citations
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December 2011 in “British Journal of Dermatology” This review discusses the influence of menopausal status on hair parameters in women without alopecia, finding significant differences in hair growth rate, percentage anagen, and hair diameter distributions, particularly in the frontal scalp.
37 citations
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June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
28 citations
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May 2012 in “Experimental Dermatology” This article discusses alopecia areata as a potential model for studying T cell-dependent autoimmune diseases and reports no new experimental findings.
26 citations
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June 2016 in “Journal of Reproductive Immunology” This study found that in women with polycystic ovary syndrome, xanthine oxidase activity is a useful marker for oxidative stress and is positively correlated with inflammatory markers and cardiovascular disease risk factors.
24 citations
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July 2018 in “British Journal of Dermatology” Contact allergies might contribute to frontal fibrosing alopecia.
24 citations
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January 2012 in “Indian Journal of Dermatology, Venereology and Leprology” This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.
24 citations
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January 1985 in “Dermatology” This study reports that OKT6-positive dendritic cells increase in hair follicles during progressive alopecia areata, suggesting a potential role in disease pathogenesis through interaction with T cells.
16 citations
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April 2020 in “JAMA dermatology” More inflammation leads to faster and worse hair loss in women with frontal fibrosing alopecia.
15 citations
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July 1998 in “Acta Dermato Venereologica” A gluten-free diet does not help hair regrowth in celiac disease patients with alopecia areata.
13 citations
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February 2012 in “International Journal of Dermatology” This case report identifies a novel nonsense mutation in the CDH3 gene associated with hypotrichosis and juvenile macular dystrophy.
12 citations
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April 2017 in “Experimental and Therapeutic Medicine” This study found that patients with active severe alopecia areata exhibited decreased CD200 expression on T and B lymphocytes, which may be linked to an imbalance in Th1/Th2 immune equilibrium.
10 citations
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September 2014 in “Australasian Journal of Dermatology” This report describes onset, regrowth, and relapse patterns in alopecia areata and proposes mechanisms to integrate into current theories, with no new clinical results.
10 citations
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January 2009 in “Elsevier eBooks” This review discusses the structure, functions, and growth cycle of human hair, emphasizing its reduced growth and protective roles, and reports no new research findings.