The Management of Postacne Scarring

August 2007 in “ Dermatologic surgery ”

Greg Goodman, Jennifer A. Baron

acne scarring pathogenesis inflammation angiogenesis fibrosis therapeutic interventions disease load lesion morphologies immunologic aspects

TLDR New treatments for acne scars are safer and more effective because we understand the causes better.

The document from 2007 discusses advancements in the treatment of postacne scarring, noting that a better understanding of the pathogenesis of acne scarring has led to the development of new techniques with more favorable risk-benefit profiles. The article aims to categorize these newer techniques according to their suitability for different grades of acne scarring, which are defined by disease load, severity, and lesion morphologies. It provides a comprehensive discussion of therapeutic interventions targeting various biological processes involved in scarring, such as inflammation, angiogenesis, and fibrosis. The document emphasizes the importance of understanding the pathogenesis, individual variability, and the inflammatory and immunologic aspects of scarring in order to develop successful treatments. These innovative techniques from the past decade are designed to minimize procedural and postoperative risks while addressing the pathological processes of scarring.

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Research cited in this study

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research Post Acne Scarring: A Review

81 citations, January 2003 in “Journal of cosmetic and laser therapy”

New techniques have improved acne scar treatment, but multiple tailored sessions are often needed.

research Long-Term Follow-Up of Leucoderma Patients Treated with Transplants of Autologous Cultured Melanocytes, Ultrathin Epidermal Sheets, and Basal Cell Layer Suspension

177 citations, November 2002 in “British journal of dermatology/British journal of dermatology, Supplement”

Transplantation is effective for stable leucoderma but not for progressive, widespread vitiligo vulgaris.

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