Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the development of liposome-based delivery systems to enhance skin wound healing, highlighting their advantages and potential applications, but reports no new clinical results.

This study reported that pentoxifylline-loaded liposomes, optimized using a statistical design method, achieved a maximum encapsulation efficiency of 84.23% and a controlled 72-hour drug release, potentially improving therapeutic delivery of the drug with limited bioavailability.

This study reported the successful development of finasteride-loaded poly(lactic-co-glycolic acid) nanoparticles, with varying encapsulation efficiencies, aiming to enhance drug delivery for hair growth while minimizing side effects, and noted that an in vivo study will follow to assess efficacy.

This review highlights the potential of extracellular vesicles derived from medicinal plants as therapeutics for diseases such as cancer and inflammation, suggesting they may enhance the clinical use of herbal preparations, despite the challenges posed by extract complexity and individual variability.

In this study, a newly engineered scaffold, PADM-MX-Ag-Si@Dox, demonstrated potential as a multifunctional biomaterial for postoperative melanoma treatment by controlling drug release, enhancing wound healing, and enabling real-time tumor surveillance through temperature, pH, and electrical stimuli.

This review discusses recent advances in using nanocarrier-loaded gels for various medical applications and reports no new clinical results, highlighting potential advantages in therapeutic strategies.

This study found that curcumin spanlastics demonstrated greater antimicrobial, antioxidant, and anticancer activities in the MCF-7 breast cancer cell line compared to curcumin alone or curcumin nanocrystals, also affecting several cancer-related protein markers and showing enhanced solubility and activity.

This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

This study found that, in mouse tail epidermis, stem cells rapidly activate and regenerate new progenitors to repair wounds, with mechanisms affecting their proliferation, differentiation, and migration.

This article reviews the design and objectives of the Rotterdam Study, as well as summarizes major findings, without reporting new results.

In this review, the authors summarize classical and recent insights into the biology and treatment of hypertrophic scars and keloids, concluding that while understanding and strategies have advanced, effective prevention and treatments remain unsatisfactory.

This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.

This review discusses mesenchymal–epithelial interactions in hair follicle development and cycling, highlighting recent insights without reporting new experimental results.

This study found that ZnO nanoparticles in topical skin products do not penetrate beyond the outer skin layers in humans, suggesting minimal safety concerns for subdermal absorption.

This forum article in BMC Biology discusses evolving views on the concept of the stem cell niche, highlighting varied mechanisms and the need for better understanding of the niche's roles and functions.

This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.

This review discusses sex-based differences in immune responses, focusing on genetic, hormonal, and microbiome factors influencing infections like COVID-19, and reports no clinical results.

This review discusses the clinical manifestations and immune response to Rhodococcus equi infection in foals but reports no new clinical results.

This study found that mice with a mutant CDP/Cux protein lacking the homeodomain showed severely impaired growth, high postnatal mortality, and reduced fertility, highlighting CDP/Cux's role in developmental regulation.

This study found that the transcription factor p63 is crucial for horizontal basal cell differentiation in the olfactory epithelium, suggesting a p63-dependent mechanism activates reserve stem cells after injury.

The study reported that combining the Follicular Closing Technique with the Franz diffusion cell is a valuable method for investigating follicular caffeine penetration in vitro, though kinetics differ from in vivo results.

This review discusses the anatomical and histological characteristics of facial fat compartments and reports no new clinical results, emphasizing a need for further research on their role in facial aging.

This review discusses the emerging "endocrine phenotype" of COVID-19, highlighting the implications for managing diabetes, obesity, vitamin D deficiency, and other endocrine conditions in affected patients.

This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.

This review discusses the challenges and contradictions in understanding nanoparticle penetration and toxicity in human skin, emphasizing the need for standardized testing and further research on particles smaller than 10 nm.

This article discusses the foundational concepts of nanotechnology and its contributions to dermatology and medicine, but does not present new research findings.

This review discusses the basic biology of apoptosis and its relevance to skin diseases, without presenting new research findings.

This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.

This study examined different polymersome systems for topical finasteride delivery and found that chitosan-decorated C7 polymersomes may enhance skin retention and provide controlled drug release compared to non-decorated systems in laboratory settings.