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The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Artificial sebum L closely mimics human sebum for drug delivery research.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

The combination of propylene glycol and Tween® 80 improves finasteride gel effectiveness.

Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.

Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.

Gallic acid and ferulic acid can be sustainably extracted for hair supplements with high efficiency and stability.

Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.

Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.

The herbal cream was found to be a safe and effective alternative for hair growth, similar to minoxidil.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.

Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.

The study found a way to improve a skin-applied minoxidil formula using a specific design method.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Polymeric nanoparticles show promise for treating skin diseases.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.