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Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

XEDAR triggers a specific signaling pathway in cells.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

Certain spices may help prevent and treat skin cancer, but more human trials are needed.

Taxol damages hair growth cells, causing hair loss.