Search

everythinglearnresearchcommunity

for

Search:↓

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Intermediate filaments are crucial for cell differentiation and stem cell function.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

Albumin and prednisone improved symptoms in a woman with Cronkhite-Canada syndrome, revealing potential genetic causes.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Sulforaphane from broccoli can help protect skin from sun damage.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.

The treatment was ineffective in humans.

Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.

Targeting colon cancer stem cells might lead to better treatment results.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.