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This study reported that Panax ginseng extract significantly inhibited DKK-1-induced catagen-like changes in human hair follicles by promoting cell proliferation and reducing apoptosis, suggesting it may help mitigate hair loss associated with DKK-1.

This study found that the twisted hair shafts characteristic of pili torti may result from uneven outer root sheath cell development, leading to irregular hair shaft modeling and twisting.

This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.

In this study, topical application of ginsenosides Rb₁ and Rd in mice increased cell proliferation in hair follicles, suggesting they may help prevent hair loss by promoting growth through p63 induction.

This study found that overexpression of antizyme in mice with activated MEK reduced skin tumor growth by inhibiting putrescine accumulation, slowing cell growth, and increasing G2/M transit time.

In this study, researchers linked SARS-CoV-2 infection to telogen effluvium in some COVID-19 patients by observing the accumulation of viral proteins in hair follicle cells, which may trigger stress responses and cell death, suggesting hair follicles as a potential target in COVID-19.

This study reported detailed three-dimensional ultrastructural observations of human hair and hair follicles using a modified preparation method, including morphological differences in hair bulb cell layers and surface projections on root sheath cells.

This case report describes a proliferating trichilemmal cyst that underwent malignant transformation, with specific keratins identified in the tumor but no epidermal keratin detected.

This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.

This case report details a rare instance of malignant proliferating trichilemmal tumour in a 60-year-old male, emphasizing the significance of histochemical and immunohistochemical markers for accurate diagnosis and differentiation from squamous cell carcinoma.

In this study, researchers observed that sodium selenite may counteract the pro-apoptotic effects of sodium fluoride on human scalp hair follicle cells in vitro.

The researchers reported that basal cell carcinoma tumor cells strongly express keratins typical of basal keratinocytes and some hair follicle components but lack differentiation markers, suggesting a follicular or pluripotent stem cell origin.

This study found that high levels of human cytokeratin 16 expression in transgenic mice lead to skin lesions and altered keratinocyte structure, suggesting potential implications for human skin disorders and wound healing.

This review discusses the historical, legal, and clinical aspects of electrolysis and thermolysis, highlighting potential risks due to the lack of standardized training for electrologists in the United States, but reports no new clinical results.

In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.

This study found that the zinc transporter ZIP10 is crucial for epidermal development, as it influences the activity of p63, promoting epidermal morphogenesis.

Keratins 8 and 14 can help identify and diagnose benign skin tumors.

This study observed that lectin-binding patterns in skin appendage tumors reveal differences in sweat gland tumors compared to normal tissues, but pilosebaceous tumors maintained a similar lectin-binding pattern to their corresponding normal structures.

In a mouse model of chemotherapy-induced alopecia, this study found that inhibiting the protein S100A8 with paquinimod alleviated hair loss and reduced oxidative stress and ferroptosis, suggesting a potential therapeutic strategy for managing this side effect in chemotherapy patients.

This study observed that the keratinization pattern of trichilemmal cysts in two Japanese women may originate from the proliferation of the outer root sheath in the follicular isthmus of anagen hairs.

This study hypothesizes that curly hair is shaped by the contraction of the Arrector Pili Muscle within the follicle, potentially modifiable through muscle-relaxing treatments, but further research is needed to confirm this mechanism.

This pilot study suggests that lovastatin may counteract stress-induced MICA expression in hair follicles and enhance MICA shedding, potentially offering a complementary approach for alopecia areata treatment.

In this study, Sox13 was identified as a novel marker for early hair follicle development and differentiation in mice, though it appears to be dispensable for overall epidermal and adnexal development.

This study observed that unpigmented keratinocytes saturate quickly with foreign substance uptake compared to pigmented melanocytes, where melanin significantly enhances binding.

This study observed that outer and inner root sheaths of human hair follicles are predominantly characterized by different glycoconjugates, suggesting a relationship between specific lectin labeling and follicle differentiation.

This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.

This study observed that epidermal growth factor and fibroblast growth factor have distinct roles in sheep skin, with EGF involved in differentiation and FGF in bulb proliferation and fiber growth.

This study found that TGF-β1 expression in follicular tumors correlates with differentiation degree and suggests its potential role alongside p63 in differentiating between sebaceous and follicular tumors.

This study found that the PPAR-γ modulator N-acetyl-GED may enhance mitochondrial function in human hair follicles, particularly in outer root sheath keratinocytes.

This study found that DECORIN promotes the proliferation and migration of outer root sheath keratinocytes in vitro and maintains the hair anagen phase in mice.