Investigation of Foreign Substance Binding in Permanent Keratinocyte and Melanocyte Cell Lines and the Suitability of Primary Cultures from Human Hair Follicles for In-Vitro Measurement of Foreign Substance Uptake in Hair

    January 2006 in “ Carl von Ossiezky University of Oldenburg ”
    Dino Magnani
    Studysummary This study observed that unpigmented keratinocytes saturate quickly with foreign substance uptake compared to pigmented melanocytes, where melanin significantly enhances binding.
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    Research cited in this study 6

    1. Amphetamine and N-Acetylamphetamine Incorporation into Hair: An Investigation of the Potential Role of Drug Basicity in Hair Color Bias Journal of Analytical Toxicology · 2001
    2. Influence of Pigmentation on the Codeine Content of Hair Fibers in Guinea Pigs Journal of Forensic Sciences · 1997
    3. Biochemical Approach on the Conservation of Drug Molecules During Hair Fiber Formation Forensic science international · 1997
    4. Differential Epithelial Outgrowth of Plucked and Microdissected Human Hair Follicles in Explant Culture Archives of Dermatological Research · 1996
    5. Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    6. Hard Keratin Intermediate Filaments and Associated Proteins 1990