This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.
56 citations
,
April 2019 in “The Plant Journal” This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.
22 citations
,
August 2015 in “PloS one” This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.
September 2025 in “Pakistan Journal of Science” This study observed that individuals with type 1 diabetes mellitus have notably lower levels of essential and trace elements like Calcium, Potassium, and Zinc in biological samples compared to non-diabetic controls.
160 citations
,
January 2017 in “Development” This study found that hypertrophic chondrocytes at the fracture callus border may convert to osteoblasts, influenced by vasculature and pluripotency gene expression.
January 2006 in “Dianzi xianwei xuebao” This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.
June 2026 in “World Journal of Clinical Pediatrics” This study highlights the importance of recognizing non-nutritional forms of rickets, which can manifest with subtle symptoms like alopecia and cataracts, and emphasizes that a comprehensive diagnostic approach, including genetic testing, can improve management and treatment outcomes.
5 citations
,
January 1976 in “Acta Dermato Venereologica” This study found that sodium and potassium hair levels may serve as sex-specific indicators, with slight differences in copper and iron content between males and females, particularly during the female reproductive period.
26 citations
,
April 1975 in “Journal of Wildlife Management” This study found that Alaskan moose hair mineral content varied seasonally and by location, with differences in magnesium, copper, and manganese levels linked to winter-killed calves.
9 citations
,
January 2013 This study found that serum levels of zinc, copper, and selenium were significantly lower in patients with alopecia areata compared to healthy controls, regardless of the number of hair loss patches.
This thesis explores the role of the actin cytoskeleton in plant cell growth, highlighting its involvement in signal transduction and the regulation of tip growth in cells like root hairs.
46 citations
,
May 2021 in “Stem Cell Research & Therapy” This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.
1 citations
,
August 2023 in “Journal of Dentomaxillofacial Science” This study found that freeze-dried homologous platelet-rich plasma (FD HPRP) increased osteocalcin levels in cultured osteoblasts, suggesting its potential to support bone regeneration in periodontal treatment.
1 citations
,
October 2017 in “Frontiers in Physiology” This article proposes a hypothesis that KRT75, a protein found in hair follicles, was evolutionarily co-opted by ameloblasts during the development of prismatic enamel in synapsids, but reports no new results.
October 2023 in “Journal of the Endocrine Society” This case report describes ALP elevation in a patient with severe OA that normalized after bilateral knee replacements, highlighting a potential link between OA and ALP levels.
9 citations
,
November 2019 in “Cell calcium” This study found that a mutation causing Stormorken syndrome in mice led to skeletal abnormalities and unusual hair growth, showcasing the STIM1 R304W protein’s role in bone development and cell fate.
28 citations
,
November 2013 in “Cell and Tissue Research” April 2016 in “Journal of Investigative Dermatology” Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.
This study found that hoof progenitor cells from fresh equine tissue have multilineage differentiation capabilities, offering insights for future progenitor cell-based hoof and dermal-epidermal tissue engineering.
6 citations
,
June 2024 in “Gels” In this study, researchers used 3D printing combined with cryogenic crosslinking to develop gelatin/oxidized alginate scaffolds and found that adding 5% hydroxyapatite improved mechanical properties and osteogenic effects, enhancing bone tissue regeneration, though 10% hydroxyapatite offered no additional osteogenic benefits and reduced shape fidelity.
512 citations
,
February 2008 in “Science” In this study, researchers found that a positive feedback loop involving Ca 2+ and RHD2 NADPH oxidase-derived ROS helps maintain growth sites, crucial for root hair development and cell shape in Arabidopsis thaliana.
3 citations
,
March 2022 in “International Journal of Trichology” This study found that nutritional supplementation with hydrolyzed collagen, amino acids, vitamins, and minerals significantly improved hair anagen/telogen ratios and hair density in telogen effluvium patients.
July 2026 in “Acta Biomaterialia” This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.
45 citations
,
June 2016 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This review evaluates the scientific literature on silicon supplements, noting that orthosilicic acid shows higher bioavailability, but emphasizes the need for further clinical studies on safety and efficacy.
1 citations
,
August 1985 in “Proceedings annual meeting Electron Microscopy Society of America” This study discusses using SEM/EDX for elemental analysis of hair samples in forensic science but notes challenges in detecting certain trace elements from raw hair.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source provides supplementary materials for the Carnivore Follicular Integrity Framework, a theoretical model proposing that animal-based diets may support hair follicle stability through several biological mechanisms. The materials include definitions, nutrient tables, and mechanistic notes but do not report empirical results.
106 citations
,
December 2015 in “Biomacromolecules” This study describes a method to create keratin hydrogels with adjustable erosion rates by mixing different ratios of keratose and kerateine, enabling controlled release of therapeutic agents like insulin-like growth factor 1.
4 citations
,
January 1989 This study found that growth affects selenium deposition in hair, nails, and other tissues of adult and weanling rats, indicating dietary and physiological factors may influence selenium levels.
248 citations
,
September 2006 in “PLANT PHYSIOLOGY” This study observed that extracellular ATP is present in Medicago truncatula and correlates with regions of active cell growth, suggesting its integral role in plant development.