10 citations
,
April 1965 in “Journal of Nutrition” Changing mineral levels in rats' diets can prevent kidney stones, affect hair growth, and influence weight gain.
45 citations
,
February 2001 in “Joint bone spine” This study found that Turner’s syndrome is associated with significant bone mass decrease due to estrogen deficiency, which can be improved with estrogen therapy, while bone issues in Klinefelter’s syndrome may benefit from early androgen therapy and possibly bisphosphonates.
May 2026 in “Signal Transduction and Targeted Therapy” This study found that rete ridge morphogenesis in mammalian skin is directed by a BMP-dependent developmental program, which is evolutionarily distinct from other known pathways controlling the development of hair follicles, sweat glands, and fingerprint ridges.
478 citations
,
September 1996 in “Proceedings of the National Academy of Sciences” This study found that overexpression of PTHrP in mice chondrocytes led to short-limbed dwarfism and delays in endochondral ossification, highlighting PTHrP's role in inhibiting chondrocyte differentiation.
5 citations
,
July 2014 in “Journal of X-Ray Science and Technology” This study suggests that hair analysis could serve as a diagnostic tool for detecting calcium channel activity, which influences hair calcium levels and may indicate calcium deficiency or related disease states.
January 1995 in “Revista de arqueología” In this study, the vitamin D analogues 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol were found to thin the living cell layer and affect differentiation marker expression in organotypic cultures of human outer root sheath cells.
2 citations
,
January 1986 in “PubMed” This study measured elemental content in anagen hair fibers of Caucasian people aged 10-69 and found average levels of sulfur, zinc, calcium, and chlorine, establishing a baseline for future research.
19 citations
,
October 2016 in “Nutrition in clinical practice” This article provides guidelines by ASPEN for managing parenteral nutrition shortages but reports no new clinical findings.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.
In this study, researchers observed that during zebrafish fin regeneration, osteoblast Erk activity, influenced by Fgf receptor signaling, forms gradients scaling with amputation length, which predicts regenerative tissue growth and skeletal structure size.
14 citations
,
February 2014 in “Nutrition in Clinical Practice” This A.S.P.E.N. document offers guidance for managing parenteral nutrition shortages, emphasizing alternative routes and careful allocation to prevent deficiencies.
33 citations
,
October 2012 in “Journal of Morphology” This study identified the distribution of keratin-associated proteins during cornification in the epidermis of reptiles, revealing unique structural characteristics in sauropsid keratin proteins compared to other vertebrates.
15 citations
,
July 2015 in “Developmental Dynamics” This study highlights the role of Orai1 in ameloblast differentiation and maturation, showing that its down-regulation affects cell proliferation and enamel formation during tooth development.
11 citations
,
July 2015 in “Gene” This study found that dihydrotestosterone (DHT) suppresses prostaglandin E2 and TGF-β induced IGF-I gene promoter activity in osteoblasts, suggesting complex interactions among bone growth regulators and potential complications from anabolic steroid use.
May 2026 in “Scientific Reports” This study found that a bioactive borosilicate glass containing Sr and Cu ions exhibited promising mechanical strength, biocompatibility, and antibacterial activity, particularly the CuSr-1 wt.% composition, suggesting potential for use in orthopedic implants and bone tissue engineering.
March 2021 in “Research Square (Research Square)” This study found that strontium ranelate may promote cartilage regeneration by enhancing chondrogenic differentiation and inhibiting the Wnt/β-catenin signaling pathway in rat models of cartilage defects.
15 citations
,
January 1988 Hair follicles have unique proteins that vary by species and are influenced by nutrition.
February 2025 in “Animals” In this review, researchers examined the molecular diversity and expression patterns of major skin appendage proteins, like keratins and EDC proteins, in tetrapods, highlighting recent findings in reptiles and birds and identifying knowledge gaps for future research.
2 citations
,
December 1973 in “Calcified tissue research” This study proposed a hypothesis for cutaneous calcinosis, suggesting that feeding DHT and subsequent epilation lead to ATP release and calcium orthophosphate formation, initiating calcification in rats.
18 citations
,
January 1977 in “Annals of Nutrition and Metabolism” This article reviews inherited mineral and trace element disturbances and reports no clinical results; it highlights conditions like hypomagnesaemia and acrodermatitis enteropathica linked to impaired nutrient absorption.
September 2018 in “BAUST Journal” 5 citations
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April 2023 in “Journal of Multidisciplinary Healthcare” This study found that chemical elements, particularly hair selenium, may indicate nutritional status in older adults, with variations observed by age and gender.
25 citations
,
January 1992 in “International Journal of PIXE” This review discusses medical conditions and therapies related to various elements, such as zinc, copper, mercury, cadmium, lead, chromium, and arsenic, without reporting new experimental results; it highlights past findings on deficiencies, toxicities, and historical cases.
2 citations
,
June 2022 in “대한스포츠의학회지” This article reviews the development of selective androgen receptor modulators and myostatin inhibitors as performance-enhancing drugs, highlighting ongoing challenges in achieving truly tissue-selective anabolic agents and reporting no new experimental findings.
18 citations
,
December 2010 in “Journal of Trace Elements in Medicine and Biology” This study suggests that alterations in copper metabolism may play a key role in the development of androgenetic alopecia in women, presenting potential targets for treatment strategies.
January 2022 in “Bio web of conferences/BIO web of conferences” This study concluded that the elemental composition of tail brush hair in newborn calves can indicate trace element supply to the fetus during the last months of pregnancy.
37 citations
,
March 2018 in “Trends in Plant Science” This review discusses the role of reactive oxygen species in regulating oscillating apoplastic pH gradients and growth in plant root hairs and pollen tubes, reporting no new experimental results.
50 citations
,
January 2016 in “The FEBS journal” This review discusses the various roles of RANK signaling in bone remodeling, immune function, and epithelial differentiation, highlighting its potential involvement in cancer mechanisms; it reports no new clinical results.