Decaying and Expanding ERK Gradients Process Memory of Skeletal Size During Zebrafish Fin Regeneration

    July 2026
    Ashley Rich, Ziqi Li, Alessandro De Simone, L. Pérez García, J.J.M. Janssen, Koichi Andō, Jianhong Ou, Massimo Vergassola, Kenneth D. Poss, Stefano Di Talia
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    Studysummary In this study, researchers observed that during zebrafish fin regeneration, osteoblast Erk activity, influenced by Fgf receptor signaling, forms gradients scaling with amputation length, which predicts regenerative tissue growth and skeletal structure size.
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