Local Positive Feedback Regulation Determines Cell Shape In Root Hair Cells

February 2008 in “ Science ”

Seiji Takeda, Catherine Gapper, Hidetaka Kaya, Elizabeth M. Bell, Kazuyuki Kuchitsu, Liam Dolan

reactive oxygen species ROS ROOT HAIR DEFECTIVE 2 RHD2 NADPH oxidase Ca2+ calcium influx positive feedback loop

TLDR Reactive oxygen species and calcium create a feedback loop that shapes root hair cells.

The study investigated the role of local positive feedback regulation in determining cell shape in root hair cells of Arabidopsis thaliana. It was found that reactive oxygen species (ROS) produced by ROOT HAIR DEFECTIVE 2 (RHD2) NADPH oxidase stimulated a Ca2+ influx, which was essential for root hair growth. In turn, Ca2+ activated RHD2 NADPH oxidase to produce more ROS at the growing point, establishing a positive feedback loop. This mechanism maintained active growth sites, influencing the ultimate form of plant cells by determining the location and stability of growth sites.

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Research cited in this study

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research Microtubules Regulate Tip Growth And Orientation In Root Hairs Of Arabidopsis Thaliana

287 citations , March 1999 in “The Plant Journal”

Microtubules help control the direction and stability of root hair growth in Arabidopsis thaliana.

research Cytoplasmic Free Calcium Distributions During the Development of Root Hairs of Arabidopsis Thaliana

317 citations , August 1997 in “The Plant Journal”

Calcium is crucial for sustaining root hair growth in Arabidopsis thaliana.

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