January 2020 in “Advances in Sexual Medicine” This study suggests that female sexual dysfunction is not significantly associated with female pattern hair loss, but it may be more strongly influenced by age and parity in premenopausal women.
April 2022 in “The Journal of Sexual Medicine” This study reports that simultaneous cystoscopy, electroejaculation, transurethral resection of ejaculatory ducts, and seminal vesiculography were safe and effective in diagnosing and treating concurrent hematospermia and anorgasmia.
34 citations
,
December 2021 in “Journal of Clinical Medicine” This review details the prevalence and management of ejaculatory disorders in men with benign prostatic hyperplasia-related urinary symptoms and highlights the importance of preserving peri-montanal tissue during treatment to maintain antegrade ejaculation.
30 citations
,
July 2009 in “Experimental and clinical endocrinology & diabetes” This article reviews the use of cyproterone acetate for conditions like prostate cancer and sexual disorders, highlighting its effects on libido but reporting no new specific trial results.
24 citations
,
July 2019 in “Reproductive Medicine and Biology” This review discusses the classification and treatment of ejaculatory dysfunction, outlining both pharmacotherapy and behavioral therapy as primary interventions, but does not present new clinical findings.
14 citations
,
March 2001 in “Psychiatric Services” This article reviews changes in men's sexual health after midlife, exploring physiologic changes, psychological factors, and various treatment options, but it presents no new clinical results.
11 citations
,
April 2023 in “Annals of General Psychiatry” This study found that males treated with serotonergic antidepressants had an increased risk of erectile dysfunction, with an adjusted odds ratio of 3.2, and the risk for post-SSRI sexual dysfunction was 0.46%, emphasizing the importance of informed consent due to these potential irreversible side effects.
8 citations
,
June 2017 in “Steroids” This study evaluated novel steroid compounds for their ability to inhibit 5α-reductase, showing that compound 16a significantly reduced rat prostate weight more than epristeride and exhibited excellent in vitro inhibitory potency, indicating its potential as a lead candidate for further benign prostatic hyperplasia drug research.
4 citations
,
June 2024 in “BMC Women s Health” This study found that infertile female patients with comorbid PCOS experience increased sexual distress linked to impaired sexual function and heightened sexual pain, indicating a need for further research into related physiological and psychological aspects.
4 citations
,
March 2022 in “Journal of The American Academy of Dermatology” This study found an association between finasteride use and increased reporting of suicidality and depression in young patients with androgenetic alopecia, potentially mediated by sexual dysfunction.
4 citations
,
April 2020 in “Reports of Practical Oncology & Radiotherapy” This review discusses the role of mental healthcare in managing sexual side effects of prostate cancer radiotherapy and highlights the importance of patient education and psychological support for improved quality of life.
1 citations
,
August 2023 in “Andrology” In this animal study, finasteride treatment altered testosterone metabolism in rat corpus cavernosum, linked to mechanisms of erectile dysfunction, but these changes were reversed after stopping the drug, suggesting post-treatment sexual side effects may relate more to central control dysfunction than peripheral issues.
March 2026 in “The Journal of Sexual Medicine” In this study, older women aged 70 and above, treated for sexual dysfunction using carefully monitored hormone therapy, reported improvements in sexual function and symptom relief, with no incidences of cancer or thromboembolic events, though some experienced breast tenderness and hair changes.
December 2025 in “Biomedicines” In this study, researchers identified two person-centered sexual function profiles among women, linked to physical and psychological factors, with PCOS showing greater, though not significant, presence in the dysfunction profile. The dysfunction was associated with higher adiposity and body-image distress.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
June 2024 in “Trends in Urology & Men s Health” This study explores the controversial condition known as post‐finasteride syndrome, observed in some men who experience lasting sexual, neurological, and psychological side effects after stopping finasteride, emphasizing its rarity and the lack of proven treatments.
April 2020 in “Online journal of complementary & alternative medicine” This article discusses the FDA approval of bremelanotide for premenopausal women with hypoactive sexual desire disorder and reports no clinical results.
September 2016 in “Oncology times” This article summarizes the ACS/ASCO Breast Cancer Survivorship Care Guidelines, which address the physical and psychosocial long-term effects of breast cancer treatments and recommend management strategies for improving women's quality of life.
September 2022 in “Translational Andrology and Urology” This study found that in young men with post-finasteride syndrome, there are potential genetic risk factors associated with psychological and sexual dysfunctions, suggesting genetic screening may be beneficial before prescribing finasteride.
90 citations
,
December 2007 in “Current Oncology” This review discusses management strategies for sexual side effects of aromatase inhibitors in postmenopausal breast cancer patients and reports no original clinical findings.
59 citations
,
August 2004 in “Human Reproduction Update” This article discusses the challenges in diagnosing female androgen insufficiency syndrome due to unreliable testosterone measurement methods but notes symptom improvement with testosterone therapy, emphasizing the need for women-specific formulations and safety guidelines.
36 citations
,
June 2014 in “PLOS ONE” This study found that men with persistent sexual side effects after using finasteride for androgenetic alopecia had higher androgen receptor expression in certain tissues compared to those who never used the drug.
35 citations
,
January 2022 in “Frontiers in Neurology” This review utilizes clinical vignettes to detail various pain syndromes associated with multiple sclerosis, including their pathophysiology and management strategies, highlighting conditions like central neuropathic pain, Lhermitte's phenomenon, and trigeminal neuralgia as they relate to different lesion types.
34 citations
,
April 2023 in “Climacteric” This review discusses the long-term effects of gender affirming hormone therapy and reports no new clinical findings, recommending a shared decision-making approach to balance benefits and risks for transgender individuals.
33 citations
,
January 2016 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the use of finasteride for androgenetic alopecia and highlights that while it is considered safe, there is concern regarding its sexual side effects, which reverse upon discontinuation.
26 citations
,
August 2016 in “Translational Andrology and Urology” This review discusses the impact of medical and surgical treatments for LUTS/BPH on ejaculatory function, highlighting that most treatments negatively affect it, except for some minimally invasive surgical therapies and specific medical therapies.
22 citations
,
November 2020 in “International Journal of Environmental Research and Public Health” This study found that hidradenitis suppurativa significantly impacts patients' sexuality, with many experiencing fear of rejection, perceived unattractiveness, and negative effects on relationships and sexual activity.
20 citations
,
April 2021 in “Journal of Womens Health” This guideline provides evidence-based recommendations for prescribing testosterone therapy to women with hypoactive sexual desire disorder, noting a moderate therapeutic benefit but highlighting limited data and regulatory challenges.
20 citations
,
April 2009 in “Fertility and Sterility” 19 citations
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February 2018 in “International Journal of Endocrinology and Metabolism” This study found that the revised 43-item PCOSQ had better validity and reliability than the original version, although further studies are needed to assess its predictive efficacy.