23 citations,
October 2005 in “Journal of The American Academy of Dermatology” Two transplant patients on cyclosporine unexpectedly developed hair loss.
12 citations,
January 2016 in “Journal of Clinical and Investigative Dermatology” Low vitamin D levels are common in people with Alopecia Areata.
1 citations,
January 2014 in “Hair therapy & transplantation” Platelet-rich plasma treatment is not very effective for chronic severe alopecia areata.
July 2019 in “The European research journal” RDW can be a useful marker for inflammation in alopecia areata patients.
286 citations,
August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.
143 citations,
January 2004 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
8 citations,
January 2013 in “International journal of trichology” Two people had unusual ring-shaped hair loss due to an autoimmune disorder.
6 citations,
November 2019 in “The application of clinical genetics” The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.
79 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.
18 citations,
June 2010 in “Cell Stress and Chaperones” Heat treatment increases hair loss in certain mice.
46 citations,
October 2018 in “JCI insight” CD8+ T cells are involved in alopecia areata and may cause disease relapse.
13 citations,
November 2012 in “Journal of The European Academy of Dermatology and Venereology” Certain factors like allergies, nail problems, and hair loss patterns can predict how well someone with patchy hair loss will respond to skin cream treatments.
October 2021 in “Dermatology Reports” Higher IL-17A levels indicate more severe alopecia areata.
September 2018 in “International Journal of Dermatology” People with alopecia areata often have lower levels of zinc and vitamin D.
April 2022 in “Research Square (Research Square)” The combination of laser and topical steroids is more effective for treating alopecia areata than topical steroids alone.
9 citations,
June 2019 in “Archives of Dermatological Research” Both topical calcipotriol and narrowband UVB improved alopecia, but combining them didn't enhance the effect on hair loss severity, despite higher vitamin D3 levels.
9 citations,
November 2012 in “Hepatology Research” A man lost all his hair permanently after hepatitis C treatment, a side effect not seen before.
9 citations,
January 2010 in “International Journal of Trichology” The study found that the cause of alopecia areata can be identified through tissue analysis, and vertical sections are enough for diagnosis.
4 citations,
April 2010 in “Expert review of dermatology” Restoring immune privilege in hair follicles could help treat certain types of hair loss.
2 citations,
April 2019 in “Acta medica Philippina/Acta Medica Philippina” People with alopecia areata often have lower vitamin D levels than healthy people.
1 citations,
April 2019 in “Acta Medica Philippina” Azathioprine may help treat severe alopecia areata, but more research is needed.
1 citations,
January 2015 in “Springer eBooks” The document says a skin condition called alopecia areata causes hair loss and stress, and is treated with strong skin creams, injections, or other therapies, but treatment success varies.
January 2024 in “Dermatology practical & conceptual” Atopic dermatitis in kids with alopecia areata can predict poor response to topical immunotherapy.
13 citations,
July 2011 in “Journal of Dermatological Treatment” Clobetasol and pimecrolimus are similarly effective for alopecia areata, but pimecrolimus has fewer side effects and is preferred for long-term use.
60 citations,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
20 citations,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
6 citations,
June 2011 in “British Journal of Dermatology” People with alopecia areata have higher levels of RBP4 protein and antibodies against it.
3 citations,
April 2010 in “Journal of Receptors and Signal Transduction” Minoxidil, a common alopecia medication, might cause eye changes due to its properties and lack of tissue selectivity.
2 citations,
November 2023 in “Frontiers in microbiology” The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.