June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reported that distinct stem/progenitor populations in the ocular surface epithelium have different cell division frequencies and respond differently to injury, with specific spatial compartmentalization and migration behaviors.
This review synthesizes current knowledge on choriogenesis, the final stage of oogenesis in insects, by exploring the role of follicle cells, regulatory mechanisms of gene expression, and the biochemical makeup of the eggshell, while also highlighting structural diversity and adaptations across insect species.
15 citations
,
November 2020 in “Development” This study found that the ocular surface epithelium in mice contains distinct stem cell populations with unique cell division dynamics that change behaviorally in response to different levels of injury.
4 citations
,
January 2024 in “Therapeutic Advances in Reproductive Health” This study found significant correlations between old and new ultrasound devices for measuring NF and ovarian volume, being the first on the African continent to reassess ultrasound criteria for PCOS.
1 citations
,
July 2025 in “Journal of Chemical Biological and Physical Sciences” This study found that women with polycystic ovary syndrome have higher rates of infertility, shorter reproductive spans, and poorer fertility outcomes compared to healthy controls.
13 citations
,
February 2010 in “Stem Cell Reviews and Reports” Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.
1 citations
,
February 2012 in “InTech eBooks”
8 citations
,
May 1941 in “Science” Mouse embryos can develop in chick embryos, but they grow smaller with some organ issues.
September 2020 in “Fertility and sterility” In this study, there was no significant difference in blastocyst quality scores between hyperandrogenic and classical PCOS patients undergoing IVF, suggesting other factors might influence the lower embryo utilization in hyperandrogenic cases.
7 citations
,
February 2025 in “Stem Cell Research & Therapy” In a study using a mouse model, HF-MSCs were reported to enhance ovarian function in cyclophosphamide-induced premature ovarian failure more effectively than HU-MSCs, potentially by preventing ferroptosis in granulosa cells via the KEAP1/NRF2/HO-1 pathway.
September 2024 in “Pigment Cell & Melanoma Research” This study found that mitochondrial fusion regulator Opa1 is crucial for maintaining melanocyte stem cells during the hair follicle cycle in mice, with Opa1 deficiency leading to impaired SCF-KIT signaling, reduced melanocyte populations, and early hair graying.
30 citations
,
July 2008 in “Reproductive Biology and Endocrinology” This study found that participation in a training workshop can significantly improve the reliability of evaluating ultrasonographic features of polycystic ovaries, suggesting standardized training modules should be used for consistent diagnosis of PCOS.
8 citations
,
August 2014 in “Biochemical and Biophysical Research Communications” The study found that over-expressing ornithine decarboxylase in the outer root sheath of the hair follicle in mice increases UVB-induced tumor growth and invasive squamous cell carcinoma compared to inter-follicular epidermal keratinocytes.
14 citations
,
March 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the flexibility and diversity of tissue stem cell systems, particularly focusing on the motility and ligand distribution of spermatogenic stem cells, without presenting new experimental results.
13 citations
,
August 2018 in “Taiwanese Journal of Obstetrics & Gynecology” This study found that serum AMH and new ultrasonographic criteria, such as FNPO ≥15 and OV ≥ 6.5 mL, effectively diagnosed PCOS, with a recommended AMH threshold of 4.7 ng/mL.
April 2026 in “Amino Acids” This study reviews prior research using transgenic K6/ODC mice and demonstrates that elevated polyamines in epithelial cells contribute significantly to skin tumor development and progression by stimulating proliferation, altering cell signaling and chromatin remodeling, and affecting immune functionality, amongst other mechanisms.
January 2011 in “Yearbook of Endocrinology”
62 citations
,
August 2018 in “Frontiers in Endocrinology” This review discusses the physiological roles of ovarian androgens in follicle development and atresia, emphasizing their contributions to polycystic ovary syndrome and normal follicle maturation but provides no new clinical results.
3 citations
,
January 2024 in “Poultry Science” This study demonstrated that FOXO3 influences feather follicle development in goose embryos by regulating the Wnt/β-catenin signaling pathway in dermal fibroblasts, resulting in changes to feather size and structure without altering follicle density.
6 citations
,
April 2017 in “Journal of Dermatological Science” This study aimed to evaluate the potential use of ovariectomized mice as a model for postmenopausal female pattern hair loss, but it reports no new results.
145 citations
,
March 2010 in “Fertility and Sterility” This study reported that ovulatory PCOS is a milder form of the condition compared to classic PCOS phenotypes, which share similar clinical and hormone characteristics.
January 2016 in “eScholarship (California Digital Library)” This dissertation reports that horizontal basal cells in the olfactory epithelium undergo symmetric divisions balanced by population asymmetry, which supports their renewal and differentiation during tissue homeostasis and regeneration.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study discovered a novel mechanism by which germ stem cells exit their niche in C. elegans, involving thin membranous protrusions from adjacent somatic gonad cells.
39 citations
,
January 2009 in “Journal of Ovarian Research” This study found moderate to poor agreement among observers assessing ultrasonographic features of polycystic ovaries, suggesting the need for standardized training modules to improve consistency.
7 citations
,
January 2022 in “Case Reports in Endocrinology” This case series observed that ovarian hyperthecosis can manifest with hyperandrogenism and insulin resistance in postmenopausal women, even when serum testosterone levels are below diagnostic thresholds, suggesting potential gaps in current diagnostic criteria.
59 citations
,
August 2007 in “Clinical Endocrinology” This review discusses the diagnostic criteria for polycystic ovary syndrome and reports no new results; the authors propose more robust criteria to address diagnostic variability and measurement uncertainty.
4 citations
,
January 2014 in “Indian Journal of Endocrinology and Metabolism” This study found that the currently established ultrasound cut-off values for diagnosing PCOS are not applicable to Indian women, suggesting that region-specific criteria improve diagnostic accuracy.
1 citations
,
January 2011 in “ScholarlyCommons (University of Pennsylvania)” In this study, researchers investigating the Drosophila testis niche system reported that Notch signaling is crucial for niche cell specification, with early gonadogenesis showing signals coming from outside the gonad to direct cell fate.
1 citations
,
February 2015 in “Revista Acadêmica Ciência Animal” This case report describes the presence of a teratoma within an equine antral follicle and suggests that the ovary maintained functionality despite the teratoma, as indicated by active antral follicles and recent ovulation.
9 citations
,
October 2013 in “Journal of Investigative Dermatology” This study found that the OVOL1 gene in mouse neonatal dermal cells is crucial for hair follicle neogenesis, suggesting it plays a significant role in maintaining trichogenicity.