Dermal FOXO3 Activity in Response to Wnt/β-Catenin Signaling Is Required for Feather Follicle Development of Goose Embryos (Anser Cygnoides)

    January 2024 in “ Poultry Science ”
    Sihui Wang, Yu Wang, Xiangman Hu … Yongfeng Sun
    Studysummary This study demonstrated that FOXO3 influences feather follicle development in goose embryos by regulating the Wnt/β-catenin signaling pathway in dermal fibroblasts, resulting in changes to feather size and structure without altering follicle density.
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    Research cited in this study 14

    1. Molecular Regulatory Mechanisms in Chicken Feather Follicle Morphogenesis Genes · 2023
    2. Establishment of a Culture Model for the Prolonged Maintenance of Chicken Feather Follicles Structure In Vitro PloS one · 2022
    3. Transcriptional Characteristics Show That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose Animals · 2022
    4. Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State Developmental cell · 2022
    5. In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos Frontiers in physiology · 2022
    6. In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Activating Wnt/β-Catenin Signaling Pathway During Chick Embryonic Period Poultry Science · 2022
    7. Molecular Signaling and Nutritional Regulation in the Context of Poultry Feather Growth and Regeneration Frontiers in Physiology · 2020
    8. Development, Regeneration, and Evolution of Feathers Annual Review of Animal Biosciences · 2014
    9. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    10. Lef1 Contributes to the Differentiation of Bulge Stem Cells by Nuclear Translocation and Cross-Talk with the Notch Signaling Pathway International Journal of Medical Sciences · 2013
    11. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    12. Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation Development · 2012
    13. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    14. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002

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