Accuracy of Anti-Müllerian Hormone and Total Follicle Count to Diagnose Polycystic Ovary Syndrome in Reproductive Women

The study investigated the effectiveness of serum anti-Müllerian hormone (AMH) levels and ultrasound criteria in diagnosing polycystic ovary syndrome (PCOS) among 55 women with PCOS and 63 control women. It found that AMH levels, follicle number per ovary (FNPO), and ovarian volume (OV) were significantly higher in the PCOS group. An AMH level of 4.7 ng/mL was identified as the optimal threshold for PCOS diagnosis, with a sensitivity of 80% and specificity of 77.8%. The study also suggested new thresholds for FNPO (≥15 follicles), follicle number per cross-section (≥7 follicles), and OV (≥6.5 mL) as reliable indicators of PCOS. A strong correlation was observed between AMH and FNPO in PCOS patients. The study concluded that AMH is a good marker for diagnosing PCOS, but international standards for AMH thresholds should be established. Limitations included a significant age difference between the groups and a sample from only one clinic, indicating the need for further research to validate these findings across diverse populations.