November 2016 in “Elsevier eBooks” This chapter reviews genetic defects in female sexual differentiation, focusing on 46,XX disorders of sex development and the impact of genetic factors and sex steroids on development, but reports no new clinical findings.
February 2010 in “ePrints Soton (University of Southampton)” This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.
February 2025 in “International Journal of Pharmaceutical Research and Applications” This article reviews the symptoms, diagnosis, and management of polycystic ovary syndrome, emphasizing lifestyle changes and medical interventions, but presents no new findings.
721 citations
,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
222 citations
,
October 2014 in “Annual Review of Pharmacology and Toxicology” This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
150 citations
,
October 2010 in “The American Journal of Pathology” This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
14 citations
,
March 1995 in “Journal of cell science” This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.
May 2026 in “Journal of Assisted Reproduction and Genetics” In this study, researchers developed and tested a novel peptide, AMHR2BP, which mimics the function of Anti-Müllerian hormone to protect ovarian follicles in mice, showing promise for preserving ovarian health during chemotherapy without causing toxicity.
August 2023 in “Frontiers in Endocrinology” This study identified novel mitochondrial DNA variations in PCOS patients from Pakistan, which may serve as genetic predisposition markers, highlighting especially the potential pathogenicity of frameshift mutations in the MT-ND2 gene.
1 citations
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August 2025 in “European journal of medical research” In this study, subclinical hypothyroidism in women with PCOS was linked to changes in the thyroid-prolactin axis and a lack of correlation between TSH and AMH, while gonadotropin levels and ovarian morphology remained unaffected, indicating the need for further prospective research.
February 2026 in “Applied Biosciences” In this study, a computational analysis of promoter regions in human fertility-related genes identified several new candidate regulatory motifs, but these require further experimental validation due to the limitations of being an in silico examination.
5 citations
,
September 2021 in “Southern African Journal of Hiv Medicine” The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
74 citations
,
January 2020 in “Frontiers in Genetics” In this study, the researchers identified key genes with differential m6A methylation involved in cashmere fiber growth, suggesting these modifications may play a significant role in this process.
6 citations
,
September 2023 in “International journal of molecular sciences” This review explores the connection between oxidative stress and polycystic ovary syndrome, discussing potential mechanisms and the possible role of antioxidants; it reports no new clinical results.
March 2026 in “Journal of Ovarian Research” This review explores the potential of platelet-rich plasma therapy for early ovarian reserve decline and premature ovarian insufficiency, indicating some ovarian function improvements in initial studies but highlighting the need for further research.
55 citations
,
May 2019 in “Journal of Endocrinology” This review summarizes research on androgens' roles in female reproductive function, noting their impact on IVF outcomes and the development of PCOS, and highlights the need for mechanism-based therapies.
14 citations
,
November 2022 in “Development” This review discusses how transposable element activation may hinder tissue regeneration and explores mechanisms to control this activity, reporting no new experimental results.
June 2020 in “Journal of genetic medicine” This article reviews neuroendocrine abnormalities in polycystic ovarian syndrome and reports no new findings, highlighting areas such as the hypothalamus-pituitary axis and genetic basis.
21 citations
,
December 2019 in “PloS one” In this study, the authors concluded that the VCD-induced follicular depletion rat model can effectively simulate the perimenopause transition, with hormonal changes distinguishing early/mid-transition from late transition to estropause.
4 citations
,
February 2023 in “Stem Cell Research & Therapy” This study found that papillary dermal fibroblast progenitors in newborn mouse skin can be isolated and cultured to generate male germline cell precursors, demonstrating their potential through differentiation into cells with meiotic capability.
April 2026 in “Biomolecules” This review highlights recent advancements in molecular understanding and treatment approaches for PCOS, including innovative drug delivery systems and AI-driven precision medicine, but provides no new clinical results.
6 citations
,
January 2015 in “Journal of regenerative medicine & tissue engineering” This review discusses the role of stem cells and tissue engineering in regeneration and transplantation, emphasizing the need for advanced technologies to improve treatments for injuries and disabilities, but reports no new results.
This study used whole-genome resequencing to analyze genetic diversity and selection in 17 rabbit breeds, identifying genes linked to traits like coat color and body size, which could inform breeding and conservation efforts.
200 citations
,
March 2023 in “Nature Reviews Molecular Cell Biology” This review discusses the role and regulation of quiescent adult stem cells in tissue maintenance and repair, focusing on molecular mechanisms and their implications for regenerative medicine, but reports no new clinical results.
6 citations
,
December 2022 in “Frontiers in Pharmacology” This review examines the potential therapeutic effects and mechanisms of quercetin for treating polycystic ovary syndrome, noting improved clinical parameters in some studies but presenting no new results.
3 citations
,
July 2023 in “International journal of molecular sciences” This review discusses the association between emotional stress-related neuropeptides and the pathogenesis of alopecia areata, reporting no new experimental findings.
1 citations
,
May 2022 in “IntechOpen eBooks” This chapter reviews the diverse and interrelated consequences of obesity on physical, metabolic, reproductive, psychosocial, and economic health without reporting any new clinical results.
1 citations
,
January 2022 in “Pakistan BioMedical Journal” This study reported that a significant number of young women in Pakistan may unknowingly have PCOS, with many experiencing irregular periods, weight gain, and increased cravings potentially linked to dietary habits.
2 citations
,
December 2025 in “Annals of Medicine” This review discusses the complex correlation between cellular senescence and PCOS, emphasizing senescence markers, mechanisms, and potential anti-senescence therapies, but reports no new clinical results.
January 2025 in “Cosmetics” In this study, the researchers found that Astragalus sinicus extracts improved wound healing, reduced oxidative stress, and activated crucial signaling pathways in dermal papilla cells damaged by dihydrotestosterone, suggesting it may be a promising ingredient for hair loss treatment.