Impact of Subclinical Hypothyroidism on Endocrine Features in Patients with Polycystic Ovary Syndrome

This study examined the impact of subclinical hypothyroidism (SCH) on endocrine features in 124 women with polycystic ovary syndrome (PCOS), dividing them into two groups: 93 with PCOS alone and 31 with both PCOS and SCH. It found that women with both conditions had significantly higher levels of TSH and prolactin compared to those with only PCOS, while other hormonal levels showed no significant differences. A moderate positive correlation between TSH and AMH was observed in the PCOS group, and a negative correlation between TSH and FSH in the PCOS with SCH group, though not statistically significant. The study concludes that SCH in women with PCOS is linked to altered thyroid–prolactin axis activity and disrupted TSH-AMH correlation, suggesting the need for further prospective studies.