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Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

AI is revolutionizing healthcare by improving diagnosis, treatment, and monitoring, but still needs close supervision.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

Shell ginger contains kavalactones that promote hair growth and have anti-cancer, anti-inflammatory, and anti-obesity effects.

Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Substances from dental stem cells might help treat hair loss.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Skin cell-derived vesicles can help heal skin injuries effectively.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.

P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.

The document summarizes recent dermatological treatments and advances in areas like pediatric care, wound healing, skin closure, light-based therapies, pigment disorders, hair loss, immunotherapy, infection management, melanoma, drug reactions, and facial rejuvenation.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.