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Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

Susan Lee Lindquist was a pioneering biologist who made significant contributions to understanding protein folding and its role in disease.

Children with cancer had slightly more unusual facial shapes than healthy kids, but not enough to easily tell them apart.

The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Different types of skin cells play specific roles in development, healing, and cancer.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Applying a special compound can promote hair growth without harmful side effects.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.