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Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

Neuregulin3 affects cell development in the skin and mammary glands.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Skin organoids from stem cells could better mimic real skin but face challenges.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

Red ginseng oil is believed to have various health benefits and is safe, but more research is needed to fully understand how it works.

Adding a second method to PROTACs could improve cancer treatment.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Allopregnanolone changes gene expression in glioblastoma cells.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.