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Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

Fatp4 is crucial for healthy skin development and function.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

Muscles can make their own androgens, which may help muscle growth.

Thyroid hormone receptors are essential for hair growth and wound healing.

T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.

Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.

The 2018 guideline for PCOS suggests new diagnostic criteria and treatments, but recognizes the need for more research.