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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.

Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.

Scientists found a new natural compound and other known compounds in Cercidiphyllum japonicum twigs, which might be useful for medicine.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Pannexin 3 is important for bone formation and the development of bone cells.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

FP-1 is a key protein in rat hair growth, active only during the growth phase.

Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.

Targeting IL-17 could help treat pattern hair loss.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

The new cream with N-acetyl glucosamine didn't change skin color after 8 weeks.

Certain drugs change freshwater snail shells to a "banana" shape.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

No CD44 in alopecia areata, present in normal and androgenetic alopecia.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Diversifying tea products can boost profits and meet global market demands.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.