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In this study, researchers observed that the absence of the vitamin D receptor or its ligand-activated transcription in mice did not affect glucose homeostasis or gene expression in islets.

In this study, KC-AD-MSCs were found to increase COL7 deposition and anchoring fibril formation at the dermal-epidermal junction in a RDEB mouse model, suggesting potential for improving skin integrity in recessive dystrophic epidermolysis bullosa patients.

This study found that deleting the Mad2l1 gene in mice leads to rapid onset of acute lymphoblastic leukemia and liver cancer due to induced chromosomal instability.

In this study, conditional inactivation of the Mad2l1 SAC gene in mice led to aggressive and lethal acute lymphoblastic leukemia and hepatocellular carcinoma, demonstrating a link between chromosomal instability and cancer development.

This study found that K6a expression in mouse sebaceous gland ducts correlates with Hedgehog signaling, suggesting a role in duct fate.

This study found that calbindin-D9k knockout mice on a maternal vitamin D-deficient and low-calcium diet developed transient alopecia, but a high-vitamin D and calcium diet in mothers reduced this effect.

Loss of Dsc3 function in the epidermis impaired cell adhesion, leading to blistering and hair loss, which suggests a potential cause of PV-like skin diseases according to this study.

This study suggests that the interaction between folliculin and plakophilin-4 (p0071) may play a role in folliculin's tumor suppressor function by regulating RhoA signaling, impacting cell migration and junction formation.

This study found that maternal exposure to artificial food coloring additives altered the expression of CYP1A1, various glutathione S-transferases, and VEGF in rat skin, which could influence skin disease development.

This study found that conventional treatments like oral dutasteride and topical/oral minoxidil are effective for male androgenetic alopecia, and it provides guidance on the relative efficacy of some alternative treatments, such as topical melatonin and rosemary oil, compared to these conventional therapies.

This study found that progesterone's antiseizure effects in mice occurred primarily through conversion to allopregnanolone, rather than through the progesterone receptor, as evidenced by results in PR knockout mice.

mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.

This study reports that AS101 induced hair growth in mice and suggests potential for treating chemotherapy-induced alopecia in humans, which was observed in case report studies with three adolescents.

Understanding skin, hair, and nails is crucial due to their complexity and impact on health.

This study found that Neuregulin3 can influence the development and differentiation of mammary glands and epidermal features in mice, potentially by inducing c-Myc and altering cell proliferation and adhesion.

The study concluded that fatty acid transport protein 4 in epidermal keratinocytes is crucial for maintaining normal skin structure, as its deficiency led to hyperkeratosis and epidermal barrier disruption in mice.

This study indicates that progesterone’s anesthetic activity in PR knockout mice is not due to progesterone receptors but is partially mediated by the neurosteroid allopregnanolone through GABAA receptor potentiation.

This study found that prostasin's proteolytic activity is necessary for normal hair follicle development in mice, but not for interfollicular epidermal development.

This study found that ectopic expression of FGF5s in transgenic Chinese Merino sheep increased wool length and greasy fleece weight compared to non-transgenic controls.

In mouse models of alopecia areata, this study found increased dilation of lymphatic vessels in affected mice, with associated changes in gene expression related to vascular growth and immune cell movement.

In this study, researchers characterized the retinal structure and function of the Oat^rhg mouse model of gyrate atrophy, finding localized atrophy without significant retina-wide functional impact, suggesting the model may be useful for testing new treatments using multimodal retinal imaging.

This paper reviews recent findings on epidermal development and stem cell regulation, listing key studies that contribute to understanding the molecular pathways involved in skin morphogenesis without reporting new experimental results.

This study found that type XVII collagen (COL17) regulates interfollicular epidermis proliferation in both neonatal and aged mice through Wnt signaling, suggesting its potential as a target for anti-aging skin strategies.

This study found that type XVII collagen is crucial for regulating epidermal cells' proliferation in mice and may be a promising target for anti-aging skin treatments.

This study found that maternal hephaestin knockout in mice leads to neonatal hair loss, likely due to low iron levels in the mother's milk.

Ectodysplasin-A1 is crucial for developing hair, teeth, and glands.

This study observed that the vitamin D receptor is crucial for hair follicle formation and altering tumor development in the Wnt signaling pathway, suggesting therapeutic potential for vitamin D analogues in related tumors.

This study found that autophagy is impaired in Birt-Hogg-Dubé syndrome-associated renal tumors and identified that the FLCN protein interacts with key autophagy components regulated by ULK1.