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New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Removing part of the vitamin D receptor stops vitamin D from working properly.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Vitamin D and calcium are important for quick and effective skin wound healing.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Blocking Prostaglandin D₂ may help treat hair loss.

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.