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Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Baicalin may help reduce excessive male hormone levels in PCOS.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

17β-estradiol can reduce inflammation in the skin.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

The Hairless gene is crucial for healthy skin and hair growth.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Mutations in certain receptors can cause diseases and offer new treatment options.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

Vitamin D receptor helps control hair growth genes in skin cells.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Vitamin D receptor is crucial for skin wound healing.