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This study found that transgenic mice overexpressing E2F1 in their epidermis developed skin tumors, confirming in vivo that deregulated E2F1 activity can contribute to tumor development.

This study observed that Trps1 gene expression in mice is precisely regulated in skin development, particularly during hair follicle morphogenesis, with distinct localization patterns in different cell types.

In this study, researchers observed that acute stress increased levels of the enzyme 5αR2 in the medial prefrontal cortex of male rats, affecting stress reactivity, but this effect was not seen in females.

This study found that a novel IKZF1 mutation, p.L188V, is linked to juvenile-onset systemic lupus erythematosus and alters B-cell activation by disrupting normal DNA binding.

This study found that AtCEPs in Arabidopsis thaliana play a role in controlling root hair growth by processing EXT proteins, with NAC1 acting to regulate their expression and influence elongation.

This study identified a novel missense MAFB variant in a family with some unaffected members, suggesting incomplete penetrance and the potential influence of modifier genes, epigenetic mechanisms, or environmental factors on MCTO phenotype.

This study identified an unexpected critical role for the FATP4 protein in skin and hair development in mice, linking it to a potential candidate gene for restrictive dermopathy in humans.

This study found that lncRNA2919 negatively impacts hair follicle regeneration by decreasing follicle depth and density in a rabbit model, suggesting a regulatory role in the hair follicle cycle through DNA methylation.

This review focuses on the role of the transcription factor Foxn1 in skin biology and discusses its potential implications for regenerative medicine, but reports no new clinical results.

In this study, miR-218-5p was found to enhance hair shaft growth and positively regulate the Wnt signaling pathway by targeting SFRP2 during skin and hair follicle development.

This study found that the transcription factor Meis2 is crucial for the maturation and innervation of sensory neurons responsible for light touch in mice, with its absence leading to reduced touch sensitivity.

This study suggests that FGF18 may enhance radioresistance in telogen hair follicles by inducing cell cycle arrest, potentially serving as a radioprotector against radiation-induced hair follicle damage.

Fgfr2b helps maintain healthy skin and prevent cancer.

This study suggests that PDRN may enhance wound healing by reducing MIR135b expression, which in turn increases FOXO1 expression in keratinocytes.

In this study, researchers found that miR-199a-3p plays a regulatory role in hair follicle development via the PTPRF/β-catenin axis and established a mouse model of alopecia areata by downregulating this small RNA, suggesting its potential value in studying alopecia diseases.

This article reviews the role of Kremen proteins as regulators in the Wnt/β-catenin signaling pathway, highlighting their significance in development and cancer, but reports no new clinical results.

This study mapped genomic copy number variation in Chinese fine-wool sheep, identifying genes involved in sensory perception, nutrient metabolism, growth, and development, and highlighting significant selection on the RXFP2 gene.

This study found that androgen binding in male rat livers involves specific androgen receptors, which decrease with castration and are inducible in female livers with testosterone.

In this study, the researchers reported that NMMHC IIA dissociates from PAR1 and activates the CREB3/ARF4 pathway, worsening thrombin-induced blood-brain barrier damage, suggesting it as a potential therapeutic target for blood-brain barrier-related diseases.

This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.

This study found that Rab5c is crucial for proper HSPC development in zebrafish embryos by regulating Notch and AKT signaling through endocytic trafficking, with both deficiency and overactivation leading to production defects.

This study revealed that nestin-expressing progenitor cells capable of becoming ORS keratinocytes are present during both hair follicle development and in adult hair follicles.

In this study, researchers discovered that fat grafting helps reduce dermal fibrosis in radiation-injured mouse skin by decreasing specific fibroblast subpopulations associated with Fra/c-Jun signaling.

In this study, researchers identified a novel genetic variant in the NR3C1 gene in a mother and her son that predicts a truncated protein, leading to glucocorticoid resistance syndrome with mild hyperandrogenic features, although no clear genotype-phenotype correlation has been established.

This article reviews the genetic mutations associated with hypohidrotic ectodermal dysplasia and reports no new clinical results; the authors highlight the roles of EDA gene isoforms and related receptors.

This review explores the role of the TMPRSS2 gene in facilitating SARS-CoV-2 infection and its potential as a therapeutic target in COVID-19 and other respiratory infections, highlighting challenges in developing selective inhibitors.

This study found that near-infrared LED therapy enhanced ATP synthesis, reduced reactive oxygen species, and promoted collagen production and hair growth more effectively than white LEDs in human skin cells and a photoaging mouse model.

This study found that deleting the FoxN1 gene in mice disrupted the 3D thymic epithelial structure and led to 2D epithelial cysts, revealing its crucial role in thymus organization but not causing athymia.

This study identified a mutation in the keratin 71 gene that causes curly hair in certain rats, advancing our understanding of hair formation.

This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.