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Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.

This study found that a specific genetic mutation in the Fgf5 gene may contribute to the long-hair trait in Angora rabbits by reducing the binding capacity of the FGF5 protein.

This study found that RAR-gamma 1 mRNA is present in multiple skin layers and structures, suggesting a role in maintaining and differentiating normal epidermis and skin appendages.

This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.

This study identified complex regulatory elements and interactions involving the Hr gene and HR protein that are crucial for hair follicle formation and cycling in mammals.

In this study, a 532 nm laser at 15 J/cm² increased the proliferation and tenogenic differentiation of tendon-derived stem cells in rats, mediated by Nr4a1 up-regulation.

This study explored how root hairs integrate opposing growth signals but did not report new conclusive findings on the activation of known molecular players in polar growth.

In this study, researchers observed that TLR3 and scavenger receptors play key roles in skin barrier repair following UVB damage, contributing to our understanding of cellular responses to skin injury.

This study suggests that subtle modifications in ribosomal RNA methylation may influence cellular physiology and contribute to ribosome specialization in senescent human dermal fibroblasts.

This study found that RANKL promotes the regeneration of type II alveolar epithelial cells in lung tissue, suggesting it may play a role in lung repair processes for diseases like COPD and fibrosis.

In this study, NREs from lentil root nodules, specifically Serratia plymuthica 33GS and Serratia sp. R6, significantly enhanced lentil growth, altered root exudation, and modulated rhizospheric microbial communities in a greenhouse setting.

This study found that HERC6 and its neighboring genes play a significant role in the cellular response of human skin to CO2 laser therapy, highlighting key biological processes related to gene expression changes post-treatment.

This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.

This study found that in early retinal neurogenesis in mice, the transcription factor Lhx2 regulates Sonic Hedgehog signaling by controlling expression of pathway genes like the co-receptors Gas1 and Cdon.

This study provided the first X-ray crystal structure of the mammalian steroid hormone reductase AKR1D1 and identified a disease-related mutant, P133R, which may impact bile acid metabolism and cause clinical symptoms.

This study found that selectively inactivating ribonucleotide excision repair in mouse epidermis leads to DNA damage, keratinocyte intraepithelial neoplasia, and squamous cell carcinoma, indicating a potential tumor-promoting mechanism related to compromised genome maintenance.

This study highlights that ZNF750, a zinc-finger transcription factor, is crucial for epidermal differentiation and barrier formation in skin by activating genes involved in lipid processing and stratum corneum development, and links ZNF750 sequence variations to skin inflammatory diseases like psoriasis.

This study found that overexpression of the intercellular adhesion protein Necl2 in hair follicle stem cells was associated with reduced cell proliferation and delayed wound healing in both cultured cells and transgenic mice.

This study suggests that Foxn1 expression in keratinocytes influences pigmentation in mice, highlighting differences in the molecular mechanisms between mouse and human pigmentation processes.

This study found that the Polycomb Repressive Complex 2, particularly its component Ezh2, is crucial in regulating dermal fibroblast differentiation and epidermal keratinocyte proliferation during murine skin development.

This study found IL-17/IL-36 signaling to be predominant in both endotypes of Netherton syndrome, with distinct molecular profiles between NS-ILC and NS-SE lesions, offering potential therapeutic targets.

This integrative literature analysis found that radiofrequency is widely used in dermatocosmetology for facial skin rejuvenation due to its high efficiency and safety, but noted a lack of comprehensive studies on radiofrequency microneedling, which may enhance safety and efficacy over traditional methods.

In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.

This study found that a human relevant potency threshold for estrogen receptor alpha agonism may serve as a health-protective screening tool, and highlights inference performance as essential for scientific confidence frameworks.

Mycophenolate mofetil improved skin condition in a man with nephrogenic fibrosing dermopathy.

This review highlights the potential of near-infrared light therapy to improve metabolic, antioxidant, and cognitive functions without adverse effects, and supports its use for visual and neurological conditions through molecular and cellular mechanisms, as reported in this source.

This review summarizes the proposed model that describes how different shapes of 1alpha,25(OH)2D3 ligands interact with the vitamin D receptor to mediate genomic and rapid responses in cells.