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This study found that Krox20 is overexpressed in scar fibroblasts and may play a role in scar formation by upregulating genes involved in tissue remodeling and wound healing.

In this study, researchers found that the protein eIF4E is crucial for keratinocyte proliferation in psoriasis, suggesting it as a potential treatment target for the condition.

This study reported no Cx30 expression in normal interfollicular human epidermis and minimal expression in some skin structures, with faint detection in porokeratosis of Mibelli patient skin.

This study found that α3β1-integrin is crucial for maintaining normal hair follicle morphology in mice, as its deficiency leads to severe abnormalities despite not affecting interfollicular epidermal differentiation.

This study found that epidermal growth factor treatment in male mice delayed normal skin development, inhibiting hair growth and follicle development by maintaining birth-level cell proliferation and differentiation for several days.

This study describes a new tissue culture method that successfully induces outer root sheath cells from hair follicles to differentiate into a multilayered epithelium with characteristics similar to normal interfollicular epidermis.

This study found that transient activation of c-Myc in transgenic mice stimulates keratinocyte proliferation and sebocyte differentiation, affecting normal epidermal and hair follicle development.

This study found that RXRα/RARγ heterodimers are necessary for retinoic acid-induced keratinocyte proliferation in the skin, while normal epidermal maintenance does not require RAR-mediated signaling.

In this study, researchers found that TSPyV T antigens can disrupt normal cell differentiation and proliferation in hair follicles and interfollicular epidermis, possibly contributing to trichodysplasia spinulosa pathology.

This study suggests that human outer root sheath cells are suitable for skin replacement, as they can form a stratified epithelium similar to normal epidermis in organotypic cultures.

This study found that activating β-catenin signaling in embryonic epidermis promoted hair follicle characteristics at the expense of normal epidermal differentiation, leading to early pigmentation and innervation.

Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.

This study found that adipokines were expressed in the epidermis, hair follicles, sebocytes, apocrine glands, and vascular endothelium of normal canine skin, but not in the dermis or hypodermis.

This study observed that S.epidermidis was more prevalent in normal skin, whereas P.acne was more common in acne lesions among Egyptian patients; antibiotic treatments may not be the most effective for acne, highlighting alternative therapies like retinoids or lasers.

This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.

This study demonstrates that overexpression of K16 in transgenic mice disrupts normal keratinization, leading to hyperkeratosis, acanthosis, and alterations in the skin's epithelial cells.

This study demonstrates that Rac1 activity is essential for normal hair follicle formation but influences hair structure and pigmentation, in terminal differentiation, through alterations in hair shaft, cuticle, and pigmentation organization.

This study found that photoepilation in mice may disrupt normal dermal wound healing and increase the risk of hypertrophic scars or keloids.

This study found that hairless dog breeds have adapted to maintain normal body and core temperatures through structural changes like a thicker epidermis and the role of melanin in thermoregulation, with genetic mechanisms involving the FOXI3 gene governing hairlessness.

This study found that EGF receptors are aberrantly regulated and persist in cholesteatoma epithelium, suggesting a hyperproliferative character compared to normal human skin.

This study found that 5α–reductase activity is higher in infrainfundibular keratinocytes compared to interfollicular epidermal keratinocytes, suggesting a potential role in acne-related follicular changes.

This study found that mutant cells in hair follicles can be tolerated or eliminated by surrounding normal tissue, suggesting the potential for wild-type cells to counteract oncogenic mutations.

This study found that in the absence of hair follicles, cutaneous wounds in mice showed delayed reepithelialization but eventually achieved normal wound closure after expanding the activated epidermis region.

The researchers reported that BCE-like changes overlying dermatofibroma show a differentiation pattern most similar to normal basal cells based on specific keratin markers.

Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.

This study reports that the monoclonal antibody BKN-1 specifically stained basal cell epithelioma cells and certain normal skin structures, indicating a similarity in keratin expression between the tumor and follicular epithelium below the isthmus portion.

This study found that in atrophic acne scars, inflammation infiltrates the pilosebaceous unit over time, affecting resident stem cells and hindering the normal regeneration of the epidermis and adnexal structures, leading to scarring.

This study found that while epidermal PLCγ1 is not necessary for keratinocyte differentiation in interfollicular epidermis, it is crucial for normal hair and sebaceous gland formation in mice.

This study suggests that Lrig1-positive cells form a previously unknown reservoir of interfollicular epidermal stem cells in adult mouse skin, influencing epidermal proliferation and hair follicle development.

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.