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390-420 / 1000+ resultsresearch Nanoemulsions for the Encapsulation of Hydrophobic Actives
This study reported the preparation of stable oil-in-water nanoemulsions that effectively incorporate ceramide-like molecules and minoxidil, suggesting these formulations may enhance distribution and availability of hydrophobic compounds in cosmetic applications.
research Lack of endocrine systemic side effects after topical application of spironolactone in man
This study found that topically administered spironolactone in healthy volunteers resulted in no detectable systemic absorption or changes in related hormone levels over 72 hours, indicating local effect only.
research Flutamide-Loaded Zein Nanocapsule Hydrogel, a Promising Dermal Delivery System for Pilosebaceous Unit Disorders
The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
research Niosomes as a vesicular carrier for topical administration of minoxidil: formulation and in vitro assessment
This study found that minoxidil-loaded niosomes with a Span 60 and cholesterol ratio of 1:2 significantly increased skin retention of minoxidil compared to control gel.
research DESIGN AND EVALUATION OF FLUCONAZOLE LOADED ANTIDANDRUFF HAIR GEL
This article discusses the formulation and evaluation of hair gels that may improve the treatment and prevention of dandruff by providing longer-lasting effects compared to traditional shampoos and lotions, but it reports no new clinical findings.
research Clinical assessment of the local tolerance and cosmetic efficacy of a topical skin care formulation used after 70% glycolic acid facial skin rejuvenation procedures in healthy female subjects: A randomized, controlled, evaluator-blind study
The moisturizing cream used after a chemical peel was well tolerated and effectively moisturized the skin.
research 856 Topical application of newly developed pseudoceramide improved both skin and hair barrier functions
Applying pseudoceramide improved skin and hair health.
research 599 Amelioration of symptoms of dry and eczema-prone skin by an oil-in-water emulsion containing a combination of a zingiber officinale root extract and cbd with antioxidative and anti-inflammatory activity in vitro
In this study, a new emulsion containing CBD and ginger root extract significantly reduced symptoms of dry and eczema-prone skin, such as erythema and itching, in a clinical trial.
research ENHANCEMENT OF FOLLICULAR DELIVERY OF FINASTERIDE IN NIOSOMALAND PRONIOSOMAL GEL FORM FOR TREATING ANDROGENETIC ALOPECIA
This study found that a proniosomal gel formulation of finasteride increased anagen hair count in male volunteers with androgenic alopecia by 42.85% compared to the control group.
research Developing a JAK Inhibitor for Targeted Local Delivery: Ruxolitinib Cream
This article reviews the JAK signaling pathway and the development of ruxolitinib cream as a targeted treatment for inflammatory skin diseases, reporting no new clinical results.
research Iontophoresis of minoxidil sulfate from hydrophilic gels for the topical treatment of androgenic alopecia
Minoxidil sulfate gel can be used to treat hair loss.
research The study of the follicle stimulating action of the cream with plant substances
The cream with plant substances can stimulate hair follicles.
research Erosive Pustular Dermatosis of the Scalp Induced by Imiquimod
An 84-year-old man got a rare scalp condition from using imiquimod cream, which was cured with systemic steroids.
research Topical tacalcitol ointment can be a good therapeutic choice in erythromelanosis follicularis faciei et colli
This study found that topical tacalcitol improved roughness and scaling in erythromelanosis follicularis faciei et colli, although it was less effective for facial erythema.
research The efficacy and safety of diphenylcyclopropenone solutions in propylene glycol and isopropanol. A comparative study of two formulas used for the treatment of 100 patients with alopecia areata
This study reports that while DCP had similar treatment efficacy in propylene glycol and isopropanol for alopecia areata, the formulation in isopropanol was better tolerated.
research Treatment of acne keloidalis nuchae and dissecting cellulitis of the scalp with diclofenac sodium gel: a case series
This article discusses the chronic inflammatory skin diseases acne keloidalis nuchae and dissecting cellulitis of the scalp, focusing on their shared etiology and differing progression, and reports no new clinical findings.
research Alopecia Totalis
This case report describes hair regrowth in a patient with alopecia totalis using fluocinolone acetonide cream applied under thin plastic films.
research Lecithin organogels as a potential phospholipid-structured system for topical drug delivery: A review
This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
research Comparison of the Efficacy of 5% Dapsone Gel and 1% Clindamycin Phosphate Gel in the Treatment of Mild to Moderate Acne Vulgaris
In this randomized clinical trial, the authors reported that after 12 weeks, 5% dapsone gel was more effective than 1% clindamycin phosphate gel in treating mild to moderate acne vulgaris, showing efficacy in 78.2% of patients compared to 52.7% with clindamycin.
research TO FORMULATE A HERBAL HAIR SMOOTHING/STRAIGHTENING CREAM USING NATURAL INGREDIENTS AND EVALUATE ITS EFFECTIVENESS ON HAIR TEXTURE
This study found that a formulated herbal hair smoothing cream using ingredients like aloe vera and coconut oil improved hair texture, such as smoothness and shine, without irritation, offering a safer alternative to conventional products.
research Effects of Depilatory Cream Formulation and Contact Time on Mouse Skin
In this study, the researchers observed that both standard body and facial depilatory creams caused significant skin injury in mice, with varying effects depending on the mouse strain and exposure time, although both formulations were effective for hair removal.
research 50570 Irritation and sensitization potential of approved topical and transdermal delivery systems – A retrospective study
Generic topical and transdermal systems usually cause minimal irritation or sensitization.
research Optimal concentration selection of active pharmaceutical ingredients in the cream-mask intended for androgenic alopecia treatment according to experimental results on paramecium caudatum biological model
This study found that optimal antioxidant properties of a cream-mask, as indicated by extended Paramecium caudatum motor activity in a toxic environment, were achieved with 10% Sophora japonica tincture and 5% Serenoa repens dry extract.
research Iontophoretic delivery of minoxidil sulfate for topical androgenic alopecia treatment
Minoxidil sulfate, delivered through iontophoresis, can be used to treat hair loss.
research Clascoterone: a new topical antiandrogen agent.
This source reports that clascoterone cream, a topical androgen receptor inhibitor, has shown effectiveness in treating facial acne vulgaris in patients 12 and older, with clinical trials indicating a favorable safety profile compared to systemic treatments, and potential for broader dermatological applications.
research Nanoparticles enhance therapeutic outcome in inflamed skin therapy
This study observed that smaller polymeric submicron particles provided more efficient selective drug delivery to inflamed skin in a mouse model, enhancing therapeutic effects while reducing systemic adverse effects.
research BRIDGING THE GAP IN ACNE MANAGEMENT: A NARRATIVE REVIEW OF CURRENT THERAPIES AND THE EMERGENCE OF CLASCOTERONE
This source describes clascoterone, a new topical treatment for acne vulgaris that blocks androgen receptors to reduce sebaceous gland activity and inflammation, offering a lower risk of systemic side effects compared to oral treatments.
research Formulation and Evaluation of Diclofenac Diethylamine Gel Using Natural Mucilages
In this research, topical gels using natural mucilages from okra and hibiscus were successfully formulated to deliver diclofenac diethylamine, with hibiscus mucilage at 10% showing the best performance as a gelling agent based on various physicochemical tests.
research FORMULASI SEDIAAN KRIM PIJAT AROMATERAPI MINYAK ROSEMARY (Rosmarinus officinalis L.) DENGAN BASIS KRIM SUSU
This study found that rosemary essential oil can be incorporated into an aromatherapy massage cream, with different oil and water ratios affecting its physical properties.