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    Bridging the Gap in Acne Management: A Narrative Review of Current Therapies and the Emergence of Clascoterone

    June 2026 in “ International Journal of Innovative Technologies in Social Science ”
    Joanna Piasecka, Bartosz Gołembiewski, Grzegorz Mulski … Anna Jaworowicz
    Studysummary This source describes clascoterone, a new topical treatment for acne vulgaris that blocks androgen receptors to reduce sebaceous gland activity and inflammation, offering a lower risk of systemic side effects compared to oral treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 12

    1. A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health Bioengineering · 2025
    2. Deciphering the Role of Androgen in the Dermatologic Manifestations of Polycystic Ovary Syndrome Patients: A State-Of-The-Art Review Diagnostics · 2024
    3. Exploring Acne Treatments: From Pathophysiological Mechanisms to Emerging Therapies International Journal of Molecular Sciences · 2024
    4. Guidelines of Care for the Management of Acne Vulgaris Journal of the American Academy of Dermatology · 2024
    5. Isotretinoin Treatment Upregulates the Expression of P53 in the Skin and Sebaceous Glands of Patients with Acne Vulgaris Archives of Dermatological Research · 2022
    6. Use of High-Dose Cyproterone Acetate and Risk of Intracranial Meningioma in Women: Cohort Study BMJ · 2021
    7. Clascoterone: First Approval Drugs · 2020
    8. Hormonal Treatment of Acne Vulgaris: An Update Clinical, Cosmetic and Investigational Dermatology · 2016
    9. Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist Drug Research · 2011
    10. New Developments in Our Understanding of Acne Pathogenesis and Treatment Experimental dermatology · 2009
    11. Androgen Action on Human Skin – From Basic Research to Clinical Significance Experimental dermatology · 2004
    12. Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002