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Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.

The document reviews key historical figures and discoveries in dermatology.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.

The document concludes that early diagnosis and a comprehensive treatment plan are crucial for managing hair loss in children, with a focus on both medical and psychological support.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Certain fungi protect skin health, but changes can allow harmful fungi to cause serious infections, needing more research for treatment and control.

Skin problems are common in lupus patients and should be treated early to prevent worsening.

Plum-blossom needling with conventional treatments improves hair regrowth in alopecia areata.

Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Regenerative medicine is effective and safe for treating vitiligo.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

Quercetin effectively treated and prevented hair loss in mice.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Certain proteins are significantly increased in the skin of people with hidradenitis suppurativa.

PRP shows promise for treating mild alopecia areata but needs more research for cicatricial alopecias.

Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.

Regulatory γδ T cells help protect hair follicles from alopecia areata and promote hair regrowth.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

Hair follicles prevent NK cell attacks to avoid hair loss.