Search

everythinglearnresearchcommunity

for

Search:↓

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Alternative treatments show promise for hair growth beyond traditional methods.

The new ELISA method is reliable and eco-friendly for checking the quality of Pueraria candollei.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Fulvestrant at 10 mg/kg does not promote hair regrowth in dogs with alopecia X.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Compound 4 is a promising treatment for hair loss with low toxicity.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Four-amino acid part makes enzyme sensitive to finasteride.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

People with no symptoms or mild COVID-19 have lower antibody levels, increasing their risk of getting COVID-19 again.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.