April 2023 in “Journal of Investigative Dermatology” This study found that isotretinoin decreases mTORC1 signaling in acne skin, suggesting that mTOR inhibitors may have potential therapeutic benefits for acne patients.
April 2018 in “Journal of Investigative Dermatology” This study found that acne lesions and nonlesional skin in mild-to-moderate acne patients showed significant Th17-skewing and increased antimicrobials, suggesting systemic targets like IL-17/IL-23/IL-36 could be therapeutic.
61 citations
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September 2010 in “Genomics” This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.
220 citations
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May 2017 in “JAMA dermatology” This study found that the skin microbiome in patients with hidradenitis suppurativa differs significantly from healthy controls, suggesting a potential link between microbial imbalance and the disease.
January 1994 in “대한피부과학회지” This study found no significant difference in androgen receptor expression between lesional and non-lesional scalp in patients with androgenetic alopecia.
