Management of Polycystic Ovary Syndrome in Adolescence

June 2004 in “ Reviews in gynaecological practice ”

Roy Homburg

polycystic ovary syndrome PCOS androgens hirsutism acne anti-androgens insulin sensitivity glucose tolerance metformin PCOS anti-androgens insulin sensitivity glucose tolerance metformin

Studysummary This review reports that treating polycystic ovary syndrome in adolescents with anti-androgens and weight loss is beneficial, and suggests that metformin may be useful for symptom management and prevention.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Polycystic ovary syndrome (PCOS) is a common cause of menstrual irregularities, acne, hirsutism, and premature pubarche in adolescents. Diagnosis can be supported by typical ultrasound findings, and it is important to assess obese adolescents for insulin sensitivity and glucose tolerance issues due to potential long-term health risks. The excess androgens in PCOS contribute to acne and hirsutism, which can have significant psychosocial impacts on teenagers. Early detection and treatment with anti-androgens are crucial, and weight loss is a key management strategy for overweight individuals. While the long-term use of metformin in adolescents is controversial, preliminary data indicate it might be beneficial for both symptomatic and preventative treatment.

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