Search
for

    Glossary Enzyme Inhibition

    reduction or cessation of enzyme activity by specific molecules

    Enzyme inhibition refers to the process by which the activity of an enzyme is reduced or stopped. This can occur through various mechanisms, such as competitive inhibition, where an inhibitor molecule competes with the substrate for the active site, or non-competitive inhibition, where the inhibitor binds to a different part of the enzyme, altering its shape and function. Understanding enzyme inhibition is crucial in fields like pharmacology and biochemistry, as it can influence drug design and metabolic regulation.

    Related Terms

    Research 10 of 1000+

    1. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    2. Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice 2017 · 16 citations
    3. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996 · 136 citations
    4. Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex Journal of Biological Chemistry · 2009 · 47 citations
    5. GC–MS Profiling, Antioxidant, Enzyme Inhibition, Molecular Docking, and ADME Investigation of the <i>n</i> ‐Hexane Extract and the Essential Oil of <i>Platycladus orientalis</i> (L.) Franco Fruits Chemistry & Biodiversity · 2026
    6. Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5<i>α</i>-Reductase: Definition of a Selective Role for Dihydrotestosterone* Endocrinology · 1986 · 53 citations
    7. Finasteride, a 5alpha-reductase enzyme inhibitor, alone and synergism with a neurosteroid reduces responsiveness to nociceptive stimuli in male rat Journal of Pain · 2009
    8. IN SILICO STUDY OF 12 PHYTOSTEROL COMPOUNDS IN MORINGA (MORINGA OLEIFERA LAMK.) SEED OIL ON 5Α-REDUCTASE ENZYME INHIBITION ACTIVITY AS ANTI-ALOPECIA International Journal of Applied Pharmaceutics · 2022
    9. 5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by supercritical carbon dioxide fluid Journal of Supercritical Fluids · 2011 · 22 citations
    10. Phenolic composition, enzyme inhibitory, and antioxidant activity of Bituminaria bituminosa Food Science and Biotechnology · 2016 · 6 citations
    All research results →

    Community 10 of 110

    1. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    2. FCE 28260: A Forgotten 5α-Reductase Inhibitor Community · 22 Aug 2024
    3. Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp Reddit · 19 May 2023
    4. Be careful when switching from Finasteride to Dutasteride because for more efficacy. Reddit · 17 Oct 2024
    5. How to BECOME a RESPONDER to Fin/Dut if you are not responding Reddit · 5 Aug 2023
    6. Stop Using Salicylic acid on your face if using minoxidil for beard growth Reddit · 2 Jun 2024
    7. what is RU for exactly? maintenance or can it cause some regrow too? Reddit · 18 Apr 2024
    8. I really hate how current hair loss treatment only rely on DHT blockers Reddit · 16 Nov 2023
    9. Oral Minoxidil and Grapefruit Juice Reddit · 5 Aug 2023
    10. A warning to those using or thinking about using Dutasteride – Follow-up Reddit · 13 Mar 2021
    All community results →

    Learn 7 of 13

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Tofacitinib JAK inhibitor pill, an immune-system drug
    3. Baricitinib JAK inhibitor pill used for severe alopecia areata
    4. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    5. Saw Palmetto Palm-berry extract taken as a supplement
    6. Rosemary Herb whose oil is used in hair care
    7. Neem Oil Oil from the neem tree, used in traditional remedies
    All learn results →