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Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Scientists found cells in hair that are key for growth and color.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Valentina Greco emphasizes the importance of combining business management with mentoring to run a successful academic lab.

Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

EGFR helps control how hair grows and forms without needing p53 protein.

The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.

Reactive oxygen species (ROS) help control plant growth and development.