This study utilized polarized light microscopy to examine hair shafts in ten children with rare genetic disorders, such as Netherton syndrome and ectodermal dysplasia, providing valuable diagnostic insights into hair thickness, composition, and structural irregularities associated with these conditions.
January 2023 in “Austin Journal of Obstetrics and Gynecology” This study found that in a sample of girls and adolescents aged 15–24 years, the prevalence of PCOS was 22.5% according to the Rotterdam criteria.
This study compiles data on the microstructural and cytotoxic properties of nano physical sunscreens, emphasizing the need for a technology platform to assess nanomaterial characteristics due to their growing use in cosmetics.
12 citations
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August 2015 in “Experimental Dermatology” This study indicated that the mineralocorticoid receptor (MR) plays a transient role in regulating epidermal differentiation during late embryonic stages, with glucocorticoid receptor (GR) potentially compensating for MR loss during the perinatal period.
December 2010 in “대한미용학회지” This study found that Polygoni multiflori Radix water extracts stimulated hair growth and hair follicle development in mice, suggesting it may be safer than minoxidil.
June 2026 in “Frontiers in Oncology” In this study, researchers found that deficiencies in Gsdma1/2/3 significantly inhibited the initiation and progression of cutaneous squamous cell carcinoma (cSCC) in mice, suggesting GSDMA's role in promoting cSCC proliferation and its potential as a therapeutic target.
29 citations
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April 2011 in “Journal of Microscopy” This study describes a modified reduction-osmication method for staining human scalp hair that improves reagent penetration and visualization of hair cortex features using transmission electron microscopy.
7 citations
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February 2024 in “ACS Applied Materials & Interfaces” This study found that PEGylated Ag₂S-ZnS@TGA-AA heteronanostructures, activated by light exposure, showed synergistic antibacterial effects against multidrug-resistant bacteria, significantly accelerating the healing of MRSA-infected wounds in comparison to untreated wounds.
December 2021 in “Figshare” This study found that BBS7 expression is crucial for maintaining Sonic hedgehog signaling activity and periodontal ligament homeostasis, suggesting its downregulation in occlusal hypofunction affects cell migration and angiogenesis.
7 citations
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January 2018 in “Neurodegenerative Diseases” This study identified a new clinical variant of adult adrenomyeloneuropathy characterized by hypoplasia and agenesis of the corpus callosum, associated with a novel ABCD1 gene mutation.
6 citations
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October 2011 in “ISRN Ophthalmology” This study found that increased serum testosterone and dehydroepiandrosterone sulphate levels may serve as diagnostic markers for seborrheic meibomian gland dysfunction in both genders.
22 citations
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February 2008 in “Journal of Neurochemistry” This study found that minoxidil prevents long-term serotonergic toxicity induced by MDMA in rats, primarily by opening mitochondrial KATP channels and involving Akt and MAP kinases in its neuroprotective mechanism.
October 2025 in “Plastic & Reconstructive Surgery” This study evaluated the safety and effectiveness of MNC-QQ cell therapy in five men with androgenic alopecia, reporting no adverse effects and improvements in hair growth, hair density, and quality of life over six months.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that although 68% of the participants were aware of minoxidil, only 42% had proper knowledge of its correct use, with common misuse leading to scalp irritation and unwanted facial hair; highlighting the need for educational interventions for safer usage.
January 2023 in “Skin appendage disorders” This review discusses the potential of low-dose oral minoxidil as a safe and effective treatment for certain hair disorders, including alopecia, but reports no new clinical results.
5 citations
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September 2018 in “Bioscience, Biotechnology, and Biochemistry” In this study, sodium thiosulfate was observed to promote hair growth in mice by encouraging hair follicles to enter the growth phase and complementing the effects of minoxidil, suggesting potential benefits for hair loss treatment.
January 2025 in “Clinical Dermatology Review” In this case report, a 16-year-old female with Netherton syndrome, a rare genetic disorder, exhibited symptoms such as skin issues, hair abnormalities, and elevated serum IgE levels. The diagnosis was supported by skin biopsy, and treatment included topical therapies, NB-UVB, and infliximab.
13 citations
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February 2019 in “Journal of Microencapsulation” This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.
February 2023 in “Journal of The American Academy of Dermatology” This publication discusses the use of low-dose oral minoxidil for treating traction alopecia but reports no new clinical outcomes; further research on its efficacy and safety is needed.
85 citations
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January 2007 in “Journal of Drug Targeting” This study found that liposomal formulations improved minoxidil delivery to skin layers compared to niosomes and a control solution, suggesting enhanced potential for topical hair loss treatment.
1 citations
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February 2024 in “Environmental health perspectives” In this study, higher concentrations of environmental metals, particularly manganese, were linked to worse self-reported attention-related behaviors in adolescents from Italy, with no significant modification of this effect by iron status.
22 citations
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October 2004 in “Journal of Investigative Dermatology” This study identified the rough coat mutation in mice, but found that LOXL is not the causal gene, although its downregulation might contribute to related phenotypic changes.
June 2008 in “Wound Repair and Regeneration” In this study, Msx-2 knockout mice showed enhanced re-epithelialization and faster wound closure compared to wild-type controls, suggesting Msx-2 may influence skin morphogenesis during wound repair.
1 citations
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January 2025 in “Regenerative Biomaterials” In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.
19 citations
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January 2013 in “Pediatrics in review” This review discusses the onset of menstruation and related challenges in young women, with a focus on primary amenorrhea, its diagnosis, and management strategies, and reports no new clinical findings.
20 citations
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November 2019 in “International Journal of Environmental Research and Public Health” This study found that high exposure to air pollutants like SO2, NO, NO2, NOx, and PM2.5 was linked to a significantly increased risk of developing PCOS in women.
254 citations
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September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
1 citations
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June 2023 in “Curēus” In this study, researchers found that 24.7% of female medical students were diagnosed with PCOS, significantly affecting their academic success and social interactions due to symptoms like BMI abnormalities and acne, suggesting that educators should enhance support and awareness to address these challenges.
January 2017 in “Springer eBooks” Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
April 2022 in “Actas Dermo-Sifiliográficas” This study describes two cases of morning periorbital edema associated with low-dose oral minoxidil for androgenic alopecia, an effect infrequently reported in the literature.