This study found no predictive link between mothers’ PCOS symptoms and the adolescent phenotype, but identified certain gene alleles associated with higher testosterone levels in affected adolescents.
19 citations
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February 2001 in “Journal of paediatrics and child health” This report documents a 14-year-old Chinese boy with mitochondrial encephalopathy, lactic acidosis, stroke-like episodes, and a de novo A3243G mitochondrial DNA mutation, highlighting the condition's multisystem involvement without ragged red fibers in muscle biopsy.
January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)” In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.
September 2024 in “Journal of the American Academy of Dermatology” This study addresses the scarcity of information on the effectiveness and safety of low-dose oral minoxidil for treating COVID-19-associated telogen effluvium, a type of hair loss observed in some patients after COVID-19 infection, but does not report specific results.
April 2026 in “Amino Acids” This study reviews prior research using transgenic K6/ODC mice and demonstrates that elevated polyamines in epithelial cells contribute significantly to skin tumor development and progression by stimulating proliferation, altering cell signaling and chromatin remodeling, and affecting immune functionality, amongst other mechanisms.
63 citations
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April 2003 in “Journal of The European Academy of Dermatology and Venereology” This study found that minoxidil topical solution was associated with a dose-related occurrence of hypertrichosis, especially facial hair, in women treated for androgenetic alopecia.
79 citations
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November 2016 in “EMBO Reports” This review evaluates methods to study stem cell division patterns, particularly in the mammary gland, and discusses genetic factors affecting division modalities and their implications for breast cancer, but reports no new results.
21 citations
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April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.
44 citations
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January 2021 in “Research” This study explored the use of manganese-doped calcium silicate nanowire-incorporated alginate hydrogels (MCSA hydrogels) for treating melanoma and promoting wound healing, finding that these hydrogels effectively ablate melanoma under near-infrared irradiation and enhance vascular endothelial cell activity for tissue regeneration.
November 2022 in “Research Square (Research Square)” This study identified key genes and pathways involved in the growth and development of forest musk deer hair follicles, providing insights into molecular regulation and laying groundwork for future research on related diseases.
July 2024 in “Journal of Investigative Dermatology” Low-dose oral minoxidil is safe for alopecia patients, even those prone to edema.
December 2021 in “Figshare” This study found that BBS7 is crucial for maintaining Shh signaling and periodontal ligament homeostasis, with occlusal hypofunction leading to its downregulation and impacting cell migration and angiogenesis.
1 citations
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June 2021 in “International journal of pharmaceutical compounding” This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.
August 2025 in “Journal of Medical and Life Science” This case-control study in Missan Province, Iraq, found that married women with PCOS had higher rates of obesity and menstrual irregularities, along with elevated testosterone, LH, and insulin levels, compared to healthy controls, highlighting significant hormonal and metabolic complications.
2 citations
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May 2014 in “PubMed” This case report describes a 10-year-old boy with a localized patch of partial alopecia and comedonal lesions, diagnosed as an atypical nevus comedonicus, and treated with topical tretinoin.
2 citations
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May 2025 in “Advanced Science” In this study, researchers developed a method to create skin organoids using spinning bioreactors, facilitating efficient high-throughput drug screening, and found that Minoxidil activates the Wnt/beta-catenin signaling pathway in these models.
28 citations
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February 2014 in “Journal of Telemedicine and Telecare” Smartphone-based teledermatology is effective for diagnosing skin diseases in the military with good accuracy.
September 2024 in “The Neurohospitalist” Careful management of chronic hyponatremia is crucial to prevent severe neurological issues.
32 citations
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March 2014 in “PLOS ONE” This study demonstrates that FMOD deficiency in mice alters TGF-β ligand and receptor expression during wound healing stages, leading to delayed wound closure and increased scar size.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research presents the Dodatek A model, elaborating on androgen function through new mathematical indices and methodological improvements, shifting focus from serum hormone concentrations to system interactions to better describe androgen activity comprehensively.
33 citations
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November 2006 in “Survey of Ophthalmology” This report discusses the various causes and clinical assessment of madarosis, emphasizing the importance of recognizing and diagnosing associated vision or life-threatening conditions, without presenting new findings.
July 2015 in “NEJM Journal Watch” This article discusses the characteristics and complications of polycystic ovary syndrome but reports no new research findings.
9 citations
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September 2022 in “Journal of Clinical Investigation” In this study, mouse models of 22q11.2 deletion syndrome showed that growth issues in small embryonic thymuses were linked to mesenchymal cells, which could be corrected by substituting with normal mesenchyme.
186 citations
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October 1957 in “A M A Archives of Dermatology” This paper presents a collection of unusual cases observed over seven years, with detailed histological descriptions but no definitive diagnoses, aiming to encourage further discussion and understanding of the disease process.
February 2023 in “Medicine in novel technology and devices” This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.
January 2024 in “Research Square (Research Square)” This study reports that adjusting the valence states of Mo in Pluronic F127-coated MoO3-x nanozymes enhances their selective H2O2-related catalytic activity, showing promise in acute kidney injury treatment and enabling real-time monitoring of therapy effectiveness through ROS-responsive photoacoustic imaging.
15 citations
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August 2008 in “Toxicology Letters” This study found that minoxidil induced cardiovascular toxicity in marmosets at higher doses than those affecting dogs, potentially due to the drug's exaggerated pharmacological effects.
March 2012 in “Korean Journal of Microscopy” This study found that nanoparticles can penetrate the skin, but artifacts produced during specimen preparation complicate accurate observation, and proposed a method for reducing errors in imaging quantum dots as tracers.
This study identified the TALE homeodomain transcription factor Meis2 as a crucial regulator for the maturation and end-organ innervation of certain mechanoreceptors in mice, with its absence leading to altered sensory neuron structure and impaired touch sensitivity.
This study utilized polarized light microscopy to examine hair shafts in ten children with rare genetic disorders, such as Netherton syndrome and ectodermal dysplasia, providing valuable diagnostic insights into hair thickness, composition, and structural irregularities associated with these conditions.