Polycystic Ovary Syndrome in Adolescents: Intergenerational, Genetic, Quality of Life, and Binge Eating Aspects. Dissertation

    October 2022
    Lāsma Līdaka
    TLDR Adolescents with PCOS have lower quality of life due to diagnosis, binge eating, and body image concerns.
    This study investigated the intergenerational, genetic, quality of life, and binge eating aspects of polycystic ovary syndrome (PCOS) in adolescents. It included 57 adolescents with PCOS and their mothers, as well as additional groups of healthy adolescents and those at risk. The research found no predictive link between mothers' PCOS symptoms and their daughters' PCOS phenotypes. Genetic analysis revealed that certain gene variations were associated with higher testosterone levels in PCOS patients. Key factors affecting health-related quality of life (HRQoL) in adolescents with PCOS included the diagnosis itself, the degree of binge eating, and body mass index percentile, with concerns about body hair and weight being significant. No difference in binge eating frequency was found between PCOS patients and controls. The study highlighted the need for further research with larger samples and longitudinal data to better understand PCOS development over time.
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