Cardiovascular Toxicity of Minoxidil in the Marmoset

    August 2008 in “ Toxicology Letters ”
    Gilles Hanton, Cécile Sobry, Nicolas Daguès … Véronique Eder
    Studysummary This study found that minoxidil induced cardiovascular toxicity in marmosets at higher doses than those affecting dogs, potentially due to the drug's exaggerated pharmacological effects.
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    Research cited in this study 9

    1. Relationship Between Serum Concentrations, Hemodynamic Effects, and Cardiovascular Lesions in Dogs Treated with Minoxidil Toxicology and Applied Pharmacology · 1996
    2. Age Dependence of the Cardiac Lesions Induced by Minoxidil in Rats Toxicology · 1996
    3. The Pharmacologic Basis of the Cardiovascular Toxicity of Minoxidil in the Dog Toxicologic Pathology · 1995
    4. Pathogenesis of Cardiovascular Alterations in Dogs Treated with Minoxidil Toxicologic Pathology · 1989
    5. A Comparative Study of Minoxidil-Induced Myocardial Lesions in Beagle Dogs and Miniature Swine Toxicologic Pathology · 1989
    6. Whole Body and Regional Hemodynamic Effects of Minoxidil in the Conscious Dog Journal of Cardiovascular Pharmacology · 1984
    7. Minoxidil: Right Atrial Cardiac Pathology in Animals and Humans Circulation · 1980
    8. Acute Cardiomyopathy Induced by the Vasodilating Antihypertensive Agent Minoxidil Toxicology and Applied Pharmacology · 1979
    9. Toxicological Studies with the Hypotensive Agent Minoxidil Toxicology and Applied Pharmacology · 1977

    Related research 1

    1. Cardiovascular Toxicity of Minoxidil in the Marmoset Toxicology Letters · 2008