Age Dependence of the Cardiac Lesions Induced by Minoxidil in Rats

    June 1996 in “ Toxicology ”
    Eugene H. Herman, Jun Zhang, Douglas P. Chadwicka, Victor J. Ferrans
    Studysummary Older rats more affected by minoxidil's cardiotoxic effects than younger rats.
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    Research cited in this study 9

    1. Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase Biochemical Pharmacology · 1990
    2. The Action of Diazoxide and Minoxidil Sulphate on Rat Blood Vessels: A Comparison with Cromakalim British Journal of Pharmacology · 1990
    3. Pathogenesis of Cardiovascular Alterations in Dogs Treated with Minoxidil Toxicologic Pathology · 1989
    4. A Comparative Study of Minoxidil-Induced Myocardial Lesions in Beagle Dogs and Miniature Swine Toxicologic Pathology · 1989
    5. Cardiac Morphologic Alterations in Acute Minoxidil Cardiotoxicity in Miniature Swine Experimental and Molecular Pathology · 1984
    6. Acute Cardiomyopathy Induced by the Vasodilating Antihypertensive Agent Minoxidil Toxicology and Applied Pharmacology · 1979
    7. Toxicological Studies with the Hypotensive Agent Minoxidil Toxicology and Applied Pharmacology · 1977
    8. Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys Journal of Pharmaceutical Sciences · 1975
    9. Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension The New England Journal of Medicine · 1973

    Related research 1

    1. Age Dependence of the Cardiac Lesions Induced by Minoxidil in Rats Toxicology · 1996